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PDE-5 inhibitors for erectile dysfunction

Viagra - your little blue friend

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Around 1 in 10 adult males suffer from ED and while it is common for the little guy to not rise to the occasion once in a while, it should not be a common occurrence. A common criminal of occasional ED is our well known friend, alcohol. So make sure to cut yourself some slack if it does happen from time to time. But if you notice difficulties in getting or maintaining an erection or reduction in libido or inability it might be time to visit your GP to determine what the cause of your ED is and how to treat it. 

ED is not a normal occurrence due to age. Yes, as you get older you might find that you need a little bit more help in the stimulation department to get yourself going, but it should not have a great effect on your sex life.

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PDE-5 inhibitors

PDE-5 inhibitors, chemically known as phosphodiesterase type 5 inhibitors are medications that block an enzyme (cGMP-specific phosphodiesterase type 5) responsible for regulating the blood flow to the body including the penis. By blocking this enzyme, it enables men to not only get an erection more easily but also to maintain this erection when sexually stimulated. 

As with many other medications, PDE-5 inhibitors were not originally designed to treat erectile dysfunction. It was developed to treat heart-related conditions such as angina and hypertension. 

PDE-5 enzyme breaks down cGMP which plays a part in relaxing smooth muscle tissue and regulating blood flow in the body such as the penile tissue responsible for erections. Blocking phosphodiesterase type 5 in the body reduces the resistance to blood flow allowing it to flow more easily into the penis with the presence of a sexual stimulus. It is important to understand that these medications do not result in random erections. Erections only occur when you are sexually stimulated and aroused.

Viagra, your little blue friend

Over 50% of men over 40 and 70% of men over 70 suffer from some degree of ED. Viagra has recently celebrated its 20 year anniversary. It also goes by its medical name of Sildenafil Citrate and is known as a type of Phosphodiesterase type 5 inhibitor (PDE-5 inhibitor). 

Viagra maintains a level of the chemical messenger cGMP in the smooth muscle cells of the penis. This messenger helps relax the muscles in the penis needed for an erection. This helps more blood flow to the penis helping it stiffen. This keeps the blood flowing to the penis keeping it up and keeping you happy. Viagra works within the hour when taken on an empty stomach and enables you to get an erection within 3-6 hours. Viagra doesn’t produce an erection that lasts 3-6 hours. If the little blue pill is taken on a full stomach after a fatty meal, it may take longer to work. However, as it works on sexual arousal, it can be taken up to 4 hours before sex. Sexual stimulation is required to achieve an erection. After sex, the erection should disappear as per normal. If the erection doesn’t go away after 4 hours make sure to visit the emergency room to avoid long term injury. Viagra takes 2 to 3 hours to leave the body but it really depends on your metabolism and can take up to 5 to 6 hours. 

Common side effects:

  • Headaches 
  • Stomach aches 
  • Flushing 
  • Runny or stuffy nose
  • Muscle pain
  • Nausea 
  • Dizziness
  • Rash 
  • Changes in vision 

Who should avoid using Viagra

Viagra should not be used if you have these medical conditions. Men who have:

  • Have severe underlying heart or liver problems
  • Suffered a stroke or heart attack recently
  • Have low blood pressure 
  • Have certain rare inherited eye conditions

Viagra vs Viagra Connect

Viagra is and has always been a prescription medication. You cannot get Viagra over the counter in pharmacies. However, due to this limitation, there were many fake Viagra counterfeits floating around the black market. These counterfeit medications lead to many side effects and posed multiple health risks to users. Recently, a non-prescriptive spin-off of Viagra was born: Viagra Connect. You can now get Viagra Connect over the counter in pharmacies without a doctor’s prescription, so you can ensure you are putting untainted medication into your body. Dr Felix offers Viagra Connect online, prescription and hassle-free. Gets yours now from a trusted UK pharmacy. 

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