Reviewed by Virginia Chachati MPharm
(2013, University College London)
GPhC Registration number: 2087654
Information last reviewed 10/04/21
Aciclovir is an antiviral medicine used to treat infections caused by the herpes virus such as cold sores. Aciclovir tablets are available on prescription or you can buy aciclovir cream over the counter at a pharmacy. Aciclovir cream is used for treating viral skin infections such as cold sores. Aciclovir cream cannot be used in a preventative capacity or for the treatment of genital herpes.
Aciclovir cream does not cure herpes or cold sores, but reduces the severity of outbreaks. This means you should feel less pain or irritation while your cold sore heals. Cold sores normally start healing within ten days, but applying aciclovir cream can help speed up this process.
Cold sores are contagious as long as you have cold sore symptoms. Therefore, if you have a cold sore, you should avoid kissing anyone from the moment you first feel a tingling sensation right up until the cold sore has completely disappeared.
Dose |
Thin layer of cream, applied every 4 hours up to 5 times a day for 5 or 10 days |
Type of Medicine |
Topical antiviral |
Mechanism |
Competitively inhibits and inactivates viral DNA processes, preventing replication |
Available Size |
2g or 10g tube |
Available Strengths |
5% |
Active Ingredient |
Aciclovir |
Price |
From £1.90 per gram |
Side Effects |
Can include burning or stinging sensations, itching,skin drying or flaking, redness of the skin, skin rashes |
The active ingredient in aciclovir cream is aciclovir. 1 g of cream contains 50 mg aciclovir (a concentration of 5%).
The inactive ingredients in aciclovir cream are: stearoyl macrolglyceries, dimeticone, cetyl alcohol, liquid paraffin, white soft paraffin, propylene glycol and purified water.
Please Note: inactive ingredients may differ between different brands of aciclovir cream. Please read the patient information leaflet provided for further details
You should apply a thin layer of aciclovir cream to the cold sore five times per day . Try to leave a four hour gap between each application. It normally takes five days for aciclovir cream to clear a cold sore infection, but you can use it for a further five days if needed. Aciclovir cream should only be applied to your skin and not inside your mouth or nose.
Use aciclovir cream as soons as the cold sore infection appears. Wash your hands with soap and water before applying aciclovir cream. Gently apply a small amount of aciclovir cream to the cold sore. You should apply aciclovir cream five times per day for five days. Try to leave a four hour gap between each application. After five days, the infection may not have cleared, so you can continue to apply the cream for five more days.
Aciclovir cream can cause side effects in some people.
Uncommon side effects, which affect less than 1 in 100 people, include:
You should not use aciclovir cream if you are allergic to any of the ingredients listed. Do not apply aciclovir cream to the inside of the mouth, nose, eyes or vagina. Therefore, you cannot use aciclovir cream to treat mouth ulcers or infections near or around your eyes. You should see your doctor if your cold sore is bigger than usual, very painful or the aciclovir cream has not worked after ten days.
If your immune system is weak or compromised, for example if you are receiving cancer treatment, have had a bone marrow transplant or are being treated for a HIV infection, seek your doctor’s advice before using aciclovir cream.
You should inform your doctor or pharmacist if you are taking, have taken or are planning on taking any other medicines, including over the counter medicines or medicines you have bought without a prescription.
Speak to your doctor for advice before using aciclovir cream if you are pregnant or planning a baby.
Speak to your doctor for advice before using aciclovir cream if you are breastfeeding.
Aciclovir can be applied as a cream, which is available to buy over the counter at a pharmacy. Aciclovir is also available as an oral medicine, such as tablets or a liquid, but only on prescription. Aciclovir cream is a treatment for cold sores, but should not be used inside the vagina, mouth, nose or eyes. For other herpes infections, such as genital herpes, or for preventing chronic outbreaks, your doctor may prescribe aciclovir tablets.
You can buy aciclovir cream over the counter at a pharmacy, but the strength of the cream may vary. However, there are some measures you can take at home to help heal cold sores:
Aciclovir is an antiviral medicine which is used to treat viral infections. Aciclovir is not an antibiotic so it cannot be used to treat bacterial infections.
Prices from:
We’re a fully regulated pharmacy, with qualified doctors and happy customers
This was my second purchase and it’s always easy quick to get what you need - will continue to use
Charlie
Quick and discreet
Excellent service and exceptional delivery - will use again
Toni