Adalat

Buy Adalat Medication For High Blood Pressure

Adalat (nifedipine) is a calcium channel blocker that’s been around for over 40 years and is a popular choice for treating high blood pressure. It’s a generally well-tolerated medication.

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90 tablet5mg£19.99
90 tablet10mg£19.99
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About

What is Adalat?

Adalat, generic name Nifedipine, is a type of medication known as a calcium channel blocker and is prescribed as a treatment for high blood pressure.

How does Adalat work?

Blood pressure is determined by the amount of blood being pumped by the heart and the resistance to blood flow in the arteries. If the arteries become narrowed, blood pressure increases as the heart is forced to work too hard to pump blood around the body. This can lead to serious health complications such as damage to blood vessels in the brain, heart and kidneys, heart failure, stroke, or kidney failure. Calcium channel blockers such as Adalat (Nifedipine) work by relaxing, and therefore expanding, the blood vessels, helping blood to flow more easily and lowering blood pressure.

Ingredients

Active ingredients

The active ingredient in Adalat is Nifedipine.

Inactive ingredients

The inactive ingredients in Adalat are propylene glycol, cellulose acetate, hypromellose, hydroxypropyl cellulose, polyethylene oxide, macrogol, magnesium stearate, shellac, titanium dioxide (E171), iron oxide (E172), and sodium chloride.

Dosage

Your doctor will decide your dose based on your individual requirements, and will aim to prescribe the lowest dose possible. Adalat is available as short-acting, immediate-release capsules, and as long-acting, slow-release tablets or capsules. The usual starting dose for immediate-release Adalat is 5 mg taken 3 times per day, and the usual starting dose for slow-release Adalat is 10 mg twice daily, or 20 - 30 mg once per day.

How to take Adalat

Take Adalat at the same time or times each day. Swallow each tablet whole with a glass of water, with or without food. If you forget to take a tablet, do not take a double dose to make up for a missed one. If you are taking 1 tablet per day, take the dose as soon as you remember as long as it is within 12 hours of the scheduled time.

Pregnancy and breastfeeding

If you are pregnant, think you might be pregnant, or are planning on becoming pregnant, speak to your doctor for advice before taking Adalat. You should not take this medication if you are breastfeeding. Your doctor may tell you that you need to stop breastfeeding in order to take Adalat.

Side Effects

Like all medications, Adalat can cause side effects in some patients. If you notice any of the following rare but serious side effects, stop taking Adalat and contact your doctor immediately:

  • Severe, sudden generalised allergic reaction, including shock and swelling

  • Other allergic reactions causing swelling under the skin, possibly including the larynx which could be serious

  • Fast heart beat (tachycardia)

  • Shortness of breath or difficulty breathing

  • Mild to moderate allergic reactions

  • Itching, rash or hives

  • A skin reaction including blistering or peeling of the skin and mucosal reactions in the mouth, nose or genital area

 

Common side effects, which may affect up to 1 in 10 people, include:

  • Headache

  • Flushing

  • Generally feeling unwell

  • Constipation

  • Swelling of the ankles or legs

 

Uncommon side effects may affect up to 1 in 100 people and include:

  • Stomach pain

  • Unspecified pain

  • Chills

  • Low blood pressure when standing up

  • Fainting

  • Irregular heartbeat

  • Dry mouth

  • Indigestion or upset stomach

  • Wind

  • Nausea

  • Muscle cramps

  • Joint swelling

  • Sleep disorder

  • Anxiety or nervousness

  • Reddening of the skin

  • Nose bleeds

  • Nasal congestion

  • Sensation of spinning or whirling motion (vertigo)

  • Migraine

  • Dizziness

  • Trembling

  • Increased need to urinate

  • Painful or difficult urination

  • Inability to achieve or maintain an erection

  • Blurred vision

  • Temporary increase in certain liver enzymes

 

The following side effects are extremely rare affecting up to 1 in 1 000 people:

  • Stomach pain or distress caused by a mass of foreign material found in the stomach which may require surgical removal

  • Difficulty swallowing

  • Abdominal pain caused by obstruction of the gut or ulcers in the gut

  • Vomiting

  • A reduction in the number of white blood cells

  • A more severe decrease in a specific class of white blood cell

  • Increased blood sugar

  • Decreased skin sensitivity

  • Drowsiness

  • Eye pain

  • Chest pain

  • Heartburn or indigestion

  • Yellowing of the skin or the whites of the eyes (jaundice)

  • Sensitivity to light

  • Small, raised areas of bleeding in the skin

  • Join pain

  • Muscle pain

Contraindications

Do NOT take Adalat if:

  • You have had a heart attack within the last month

  • You get a sudden angina attack

  • You have unstable angina

  • You are allergic to nifedipine or any similar medications, or to any of the ingredients of Adalat

  • You are taking Rifampicin

  • You have a liver disease that prevents your liver from working properly

  • You have inflammation of the bowel or intestines, such as Crohn’s disease

  • You have an obstruction or narrowing of your intestines

  • You have ever had an obstruction in the gullet

  • You have been told that you have a narrowing of the aortic heart valve

  • You have ever had a collapse caused by a heart problem, during which you become breathless and pale, and had a cold sweat and a dry mouth

  • You have a ‘Kock pouch’ in your gut

  • If your blood pressure continues to rise despite treatment

 

Before taking Adalat, inform your doctor and take particular care if any of the following applies to you:

  • You have low blood pressure and were prescribed Adalat for angina

  • You have a heart condition where your heart cannot cope with increased strain

  • You are pregnant

  • You are breastfeeding

  • You are diabetic

  • You are on kidney dialysis

  • Your liver is not working properly

 

When taking Adalat, tell your doctor if:

  • Your angina becomes worse over a matter of hours or days

  • You have chest pains after taking your first dose of Adalat

  • You notice increased breathlessness

  • If you notice swelling of the ankles

  • If you are giving a urine sample. Adalat may interfere with the results of some tests

  • If you are to have a barium contrast x-ray

  • If you are a man who has been unable to father a child, as Adalat has been shown to impair sperm function.

Drug interactions

Before taking Adalat, tell your doctor if you are taking or have recently taken any other medications, including those purchased over the counter without a prescription. In particular, tell your doctor if you are taking or have recently taken:

  • Other medicines used to treat high blood pressure

  • Rifampicin

  • Cimetidine

  • Digoxin, diltiazem, quinidine or beta-blockers

  • Quinupristin/dalfopristin

  • Phenytoin, carbamazepine or valproic acid

  • Cisapride

  • Magnesium sulphate injections during pregnancy

  • Erythromycin

  • Ketoconazole, itraconazole or fluconazole

  • Indinavir, nelfinavir, ritonavir, saquinavir or amprenavir

  • Fluoxetine or nefazodone

  • Tacrolimus

  • Phenobarbital

Food and drink

You can take Adalat with or without food. However, you should avoid drinking grapefruit juice while taking Adalat, beginning 3 days before treatment, as this may increase blood levels of Nifedipine.  

Treatment Options

Alternatives to Adalat

There are a variety of treatments for high blood pressure and your doctor will be able to decide which is best for you. Other calcium channel blockers include Felodipine, which is taken in the morning and slowly releases throughout the day, Lacidipine, which may not be suitable for more severe forms of angina, and Lercanidipine, which needs to be taken on an empty stomach and is more likely to cause side effects. Alternatively, a doctor may chose to prescribe an angiotensin II receptor blocker (ARB), such as Valsartan, Candesartan and Losartan, or a angiotensin converting enzyme (ACE) inhibitor, such as Enalapril, Ramipril or Perindopril. ARBs and ACE inhibitors both work by interfering with the activity of the hormone angiotensin II, which is involved in the narrowing of blood vessels. However, these options are thought to be less effective in patients over the age of 55 and in patients of Afro-Caribbean descent. Other options are Beta-blockers, which block the angiotensin II hormone and also lower the heart rate, and diuretics, which aid the relaxing of blood vessels and are sometimes taken in combination with the ACE inhibitor Enalapril.

Lifestyle changes to make when taking Adalat

Alongside treatment, there are some lifestyle changes you should make to help reduce blood pressure and improve your overall wellbeing. A major cause of high blood pressure is high salt intake, so keep an eye on the salt content of any pre-prepared food you eat and try to limit your intake to below the recommended maximum of 6g per day. Cut back on saturated fats and fatty cuts of meat, and try to include plenty of fruit and vegetables, wholegrains and lean meats in your diet. If you haven’t already done so, quit smoking, and tr to reduce the amount of alcohol you drink to below 14 units per week. Exercising regularly will help to keep your heart and blood vessels in good condition and can also contribute to reducing stress, another known cause of high blood pressure. Try to reduce the impact of stress in your life by taking daily walks, spending time with friends and family and finding time to relax where possible. 

Q&A

How long does Adalat take to work?

Adalat begins to work immediately, but it may take a couple of weeks to take full effect. If you are taking Adalat for high blood pressure, you are unlikely to have symptoms and therefore will probably not notice the effects of Adalat. Your doctor may wish to check in with you regularly to monitor your blood pressure.

Will I need to take Adalat forever?

Treatment with Adalat is usually long-term, and patients often take it for the rest of their life.

Can I take Adalat before surgery?

If you are scheduled to undergo surgery, you should tell the surgeon beforehand that you are taking Adalat. You may be advised to come off of Adalat 36 hours before surgery to prevent your blood pressure from becoming too low.

Will Adalat affect my sex life?

In up to 1 in every 100 male patients, Adalat may cause problems with achieving or maintaining an erection.

Will Adalat affect my fertility

There is no evidence to suggest that Adalat affects fertility.

Will Adalat affect my contraception?

Adalat itself will not affect your contraception. However, some types of hormonal contraception, such as the combined contraceptive pill, are not recommended for use in women with high blood pressure. Speak to your doctor for advice on which contraceptives are safest for you.

Can I drink alcohol with Adalat?

You can drink alcohol with Adalat, but it may increase the blood pressure-lowering function of the drug, making you feel dizzy or tired. It is best to avoid drinking alcohol in excess when taking this medication.

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