Aknemycin Plus

Buy Aknemycin Plus online from a UK Pharmacy

  • Acne treatment that will help clear your skin in 9 to 12 weeks

  • Contains a combination of an antibiotic and a retinoid

  • Available from £19.80 + prescription fees and delivery costs

Our prices

Strength Quantity Price Stock
4.0%/0.025%1 x 25ml bottle£19.80In Stock
Prices exclude a prescription fee. This treatment requires a quick online consultation,
which a doctor will review to determine if a prescription is appropriate.

Safe and discreet

  • Safe and regulated treatments
  • 100% discreet and confidential
  • UK qualified doctors
  • Fully registered UK pharmacy


Virginia Chachati

Reviewed by Virginia Chachati MPharm
(2013, University College London)
GPhC Registration number: 2087654

Information last reviewed 24/06/2021


What is Aknemycin Plus?

Aknemycin Plus is an acne treatment you apply directly onto your skin. It helps clear your skin and reduce the appearance of spots and pimples. Aknemycin Plus contains an antibiotic called erythromycin and tretinoin which is a retinoid.

How does Aknemycin Plus work?

Aknemycin Plus works effectively to treat acne with its two active ingredients. The antibiotic, erythromycin, reduces redness and inflammation by killing bacteria to stop acne from spreading. Tretinoin is a retinoid that clears your skin by getting rid of blackheads. It also encourages your skin to peel and gets rid of hard dead skin cells.

How long does Aknemycin Plus take to work?

Aknemycin Plus can take two weeks to work before you notice your skin improving. At first, your skin may become red or irritated, but this is a sign the treatment is working. The full Aknemycin Plus treatment course is usually 9 to 12 weeks.

Is Aknemycin Plus safe for long term use?

Aknemycin Plus is designed to be used for 9 to 12 weeks. You should not use it for longer than prescribed by your doctor or pharmacist.

Does Aknemycin Plus cure acne?

Aknemycin Plus is an effective treatment for acne. You may need to continue to use acne treatments such as cleansers and creams to prevent spots from coming back. For many people, acne is temporary but breakouts can happen again in the future.

Ankemycin Plus summary


Apply to the face one or two times per day

Type of Medicine

Macrolide antibiotic with a topical retinoid


Erythromycin prevents bacterial synthesis of compounds essential to replication and tretinoin promotes cell detachment and enhances shedding, preventing pores from becoming blocked with dead skin cells

Available Size

25ml bottle

Available Strengths


Active Ingredient

Erythromycin and tretinoin


From £19.80

Side Effects

Can include temporarily alters skin tone, peeling, skin irritation, skin redness, burning, photosensitivity, rash


Active ingredients

The active ingredients in Aknemycin Plus are erythromycin and tretinoin.

Inactive ingredients

The inactive ingredients in Aknemycin Plus are ethanol, glycerol and copolyvidone.

Which ingredients can cause an allergic reaction?

As this medication contains alcohol, it can irritate the skin after application and you may experience a sore, dry or burnt sensation or see peeling. In very rare cases these symptoms may also be an expression of an allergic reaction so it is important to get this checked with a doctor. In the meantime, stop using the medication. 


How to use Aknemycin Plus

Aknemycin Plus is a liquid that comes in a bottle with a foam applicator pad on top. Before you can use Aknemycin Plus, you need the liquid to soak into the foam applicator pad. To do this, press the end of the screw cap against the foam applicator pad until you feel it click into place. Turn the whole bottle upside down to soak the foam applicator pad with Aknemycin Plus. Then you can smoothly and gently apply Aknemycin Plus to your face once or twice a day.

Aknemycin Plus dosage

Aknemycin Plus should be applied to the skin one or two times per day. Always use Aknemycin Plus as your doctor has prescribed.

How long should I use Aknemycin Plus for?

Aknemycin Plus is normally used for 9 to 12 weeks. Your doctor or pharmacist will tell you how long you should use Aknemycin Plus.

What should I do if I use too much Aknemycin Plus?

If you use too much Aknemycin Plus your skin can become dry, red or irritated. If this happens, do not use Aknemycin Plus until your skin feels better. Try to wash off any extra Aknemycin Plus and use a high SPF sunscreen during the day to protect your skin from sunlight.

What should I do if I forget a dose of Aknemycin Plus?

If you forget to use Aknemycin Plus, apply it as soon as you remember. Never double up the amount you need to use to make up for missing a dose of Aknemycin Plus.

Side Effects

Aknemycin Plus side effects

When you start using Aknemycin Plus, your skin might feel like it is getting worse. This is temporary and it is a sign that the treatment is working. 
Other side effects may include: 

  • Skin irritation 
  • Soreness 
  • Dry skin 
  • Burning 
  • Peeling 
  • Temporarily altered skin tone 
  • Photosensitivity (being sensitive to sunlight)
  • Red, scaly rash with bumps under the skin - if this happens see a doctor straight away


You should not use Aknemycin Plus if: 

  • You are allergic to any of the ingredients 
  • You have acute eczema 
  • You have rosacea 
  • You have sunburn 
  • You are using any other medicines which can cause skin irritation 
  • You have a family history of cutaneous epithelioma, a form of skin tumour 
  • You are pregnant or planning a baby
  • You are breastfeeding

Drug interactions

Let your doctor or pharmacist know if you are taking any other medicines before using Aknemycin Plus. Take extra care if you are using any of these treatments alongside Aknemycin Plus:

  • Other treatments you are applying on your skin
  • Medicated soaps or cleansers 
  • Abrasive skin products (like exfoliators)
  • Skin products that are strongly astringent or drying 
  • Skin products with high amounts of alcohol, acidic ingredients, citrus or spices 
  • Anything containing sulphur, resorcinol, benzoyl peroxide, azelaic acid or salicylic acid

Aknemycin Plus and pregnancy

You should not use Aknemycin Plus if you are pregnant, breastfeeding or trying for a baby. Speak to your doctor for an alternative acne treatment option.

Treatment Options

Can I use other acne creams or cleansers while using Aknemycin Plus?

You should not use other acne creams or cleansers while using Aknemycin Plus. It can cause further skin irritation and dryness.

Alternatives to Aknemycin Plus

For mild acne, there are alternative treatment options available over the counter. However, if your acne is moderate to severe, the following medicines are available on prescription from Dr Felix: 

  • Antibiotic creams
  • Retinoid creams
  • Azelaic acid 
  • Combined contraceptive pill 
  • Antibiotic capsules or tablets
  • Isotretinoin 
  • Benzoyl Peroxide gel

You should not use toothpaste to dry out spots as it can cause skin irritation.

How to cope with acne

Acne can be difficult to live with given the impact it has on your physical appearance. If you experience low self-esteem because of acne, then it's important to remember that many people feel this way too. Try giving your treatment time to work. It can be frustrating when you don't see instant results, but all acne treatments require time to reduce the appearance of spots. Talking to people about how you feel and reaching out for support can help.

How can I treat acne naturally?

There are natural home remedies that can clear up spots caused by mild acne. These include: 

  • Tea tree oil 
  • Witch Hazel 
  • Manuka Honey with a high UMF value

However, for moderate to severe acne, you may need to try an over the counter acne treatment, or a prescription medicine such as Aknemycin Plus from Dr Felix.


What causes adult acne?

Hormonal changes can cause acne in young people and adults. This can trigger the skin to produce excess oil. For example, during puberty, pregnancy and menstruation. Using makeup that clogs pores can also lead to a buildup of bacteria which can cause spots.

What are the different types of acne?

There are six different types of acne. These are: 

  • Blackheads- which look like small black bumps on the surface of the skin caused by the pigmentation of the hair follicle. They may also be yellow in colour
  • Whiteheads- these are similar to blackheads but firmer to touch and do not produce pus if you squeeze them
  • Papules- these are tender, sore, red bumps 
  • Pustules- tender red bumps which have a white coloured build-up of pus in the middle 
  • Nodules- these are hard lumps built up under the skin's surface and often feel painful 
  • Cysts- these are large pus-filled lumps that look like boils

Cysts and nodules are signs of severe acne and are more difficult to treat. Cysts are most likely to leave permanent scars.

Can I wear makeup while using Aknemycin Plus?

You can wear makeup while using Aknemycin Plus. After you apply Aknemycin Plus, give it a few minutes to sink in. Then you can moisturise your skin and put on your makeup. Try to use non-comedogenic makeup which won't clog up your pores. Always remove your makeup before going to bed. 

Will my acne scars heal?

Acne can leave scars, especially if you have cysts and nodules. Most acne scars will gradually fade after a couple of weeks or months but some can be permanent. 
The three types of acne scars are:

  • Ice pick scars- which leave holes in the skin's surface 
  • Rolling scars- where scar tissue forms underneath the skin leaving an uneven appearance 
  • Boxcar scars- round, crater-like grooves in the skin 

Treatment for acne scarring is not available on the NHS and can be expensive. Options include: 

  • Dermabrasion (removing the top layer of the skin)
  • Laser treatment 
  • Punch excision (where the scar is surgically removed)
  • Punch elevation (where the appearance of the scar is altered so it is less noticeable) 
  • Punch grafting (where the scar is removed and replaced with skin taken from elsewhere on the body)

How can I get rid of acne fast?

There is no quick fix for acne as your skin needs time to generate new cells and heal. Treatments such as Aknemycin Plus can be effective in clearing your skin but they take time to work.

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