Colofac is a brand name for the drug Mebeverine, which is used to alleviate the symptoms of irritable bowel syndrome (IBS). While the exact cause of IBS is not always known, it is often related to abnormal muscle contraction or inflammation in the intestine. This can be triggered by stress, hormones or even some foods, and common symptoms of IBS include stomach cramps, bloating, diarrhoea or constipation.
Colofac contains mebeverine hydrochloride, a type of medicine known as an antispasmodic. It works by relaxing the muscle wall of the intestine, preventing irregular muscle spasms and relieving symptoms such as cramps, bloating, diarrhoea and constipation.
Most people who suffer with IBS experience regular flare ups rather than constant symptoms. Unless otherwise advised by a doctor, it is best to take Colofac when needed (during a flare up) rather than all the time. For best results, take one tablet about 20 minutes before a meal, but no more than 3 times per day. Colofac aims to clear up the symptoms of IBS within 2 weeks. If your symptoms continue for longer than 2 weeks, speak to your doctor for advice.
The active ingredient in Colofac is mebeverine hydrochloride.
The inactive ingredients of Colofac are lactose, starch, povidone, talc, magnesium stearate, sucrose, gelatin, acacia and carnauba wax.
The recommended dose is 1 tablet 3 times a day before meals.
Swallow one Colofac tablet with water about 20 minutes before a meal, no more than 3 times per day. If symptoms improve, you can lower your dose to 2 or 1 tablet/s per day. This medication should be used when needed (during a flare up of IBS) and, unless otherwise instructed by a doctor, not all the time. If symptoms do not improve after 2 weeks of taking this medication, speak to your doctor for advice.
Side effects of this medication are rare. However, if you are taking Colofac and experience a severe allergic reaction (swelling of the face, neck, tongue or throat and/or difficulty breathing) stop taking the medication and contact a doctor at once. Less serious side effects can include a skin rash or red itchy skin. Speak to a doctor or pharmacist if you are concerned about these side effects.
Do NOT start taking Colofac if you are allergic to any of the ingredients listed above. This medicine is not normally recommended for use in children under the age of 10.
You should consult your doctor before taking Colofac if:
Speak to a doctor or pharmacist before taking Colofac if:
There are no known interactions of Colofac with other medicines.
It is safe to drink alcohol while taking this medication.
Little is known about the risks of taking Colofac while pregnant. Speak to your doctor for advice if you are pregnant or planning on becoming pregnant before taking this medication.
The active ingredient in Colofac, mebeverine hydrochloride, is also available in the form of dispersible sachets sold under the name Fybogel Mebeverine. This medication also includes the active ingredient ispaghula husk, which is a natural prebiotic that promotes the growth of healthy probiotics in the gut and a mild laxative. Colpermin capsules contain peppermint oil, which acts as a natural spasmodic, and are an effective alternative to Colofac. It is of note that Colpermin capsules also contain peanut oil and are therefore unsuitable for use in patients with a peanut allergy.
Colofac is used to treat IBS in adults and children over 10 years of age. In special cases, it may sometimes be used to treat intestinal spasms in children younger than 10 years of age.