Dovonex

Buy Dovonex for Treatment of Psoriasis

Order Psoriasis treatments online from Dr Felix Online Doctor and Pharmacy. We offer advice and treatments for a range of skin conditions.

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Strength Quantity Price
50 mg/g1 tube23.40
50 mg/g2 tubes36.00
50 mg/g3 tubes46.80
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About

What is Dovonex?

Dovonex belongs to a group of medications called antipsoriatics. It is an ointment containing the active ingredient Calcipotriol, and is applied topically to the skin to treat cases of Psoriasis.

How does Dovonex work?

Dovonex is prescribed to treat the symptoms of Psoriasis, a common skin condition caused by an increase in the production of skin cells and characterised by the appearance of red, flaky patches on the skin. Dovonex contains the active ingredient Calcipotriol, a form of Vitamin D, and works locally by slowing the production of skin cells and reducing inflammation. Vitamin D analogues such as Dovonex can be used instead of or in combination with corticosteroids in the treatment of Psoriasis.

How long does Dovonex take to work?

If Dovonex is applied daily, you should start to see an improvement in your symptoms about 2 weeks after starting treatment.

Ingredients

Active Ingredients

The active ingredient in Dovonex is Calcipotriol.Each gram of Dovonex contains 50 micrograms of Calcipotriol.

Inactive Ingredients

The inactive ingredients in Dovonex ointment are disodium edetate, disodium phosphate dihydrate, DL-a tocopherol, liquid paraffin, macrogol (2) stearyl ether, propylene glycol, purified water and white soft paraffin. 

Dosage

Your doctor will decide on your dose depending on your age and the severity of your symptoms. Dovonex is usually applied twice daily without exceeding 100 grams per week. Children over the age of 12 should not exceed 75 grams per week, and children between the ages of 6 and 12 should not use more than 50 grams of Dovonex per week. 

How to use Dovonex

Always use Dovonex as prescribed by a doctor or pharmacist. This ointment is a topical treatment and should not be swallowed or applied to the face. Wash your hands thoroughly, remove the cap from the tube and use the point on the back of the cap to pierce the seal of the tube. Apply a generous layer of ointment to the affected area and rub into the skin gently. Unless you are applying Dovonex to the skin of your hands, you should wash your hands thoroughly after use to prevent spread to other parts of the body. When using a moisturiser, you should wait until it has been completely absorbed before applying Dovonex. 

 

If you use too much Dovonex, inform your doctor straight away. Excessive use of this treatment may cause an increase in the level of calcium in your blood. If you forget to use Dovonex, use it as soon as your remember and apply your next dose at the usual time. 

Side Effects

Like all medications,Dovonex can cause side effects in some patients. If you experience any of the following rare but serious side effects, stop taking Dovonex and seek immediate medical attention:

  • Signs of a severe allergic reaction, including difficulty breathing, swelling of the face or skin around the eyes, and a severe rash which may include blistering or bleeding of the skin

  • Signs of an increase of calcium in the blood or urine, including an increased need to pass urine, feeling of thirst or loss of appetite, dry mouth or metallic taste, a feeling of weakness or pain in your muscles or bones, headache, abdominal pain, nausea, and constipation.

 

The following common side effects of Dovonex may affect up to 1 in 10 people:

  • Skin irritation

  • Worsening of Psoriasis symptoms

  • Dermatitis

  • Redness

  • Flaking of the skin

  • Burning or stinging sensation

  • Itchy rash and skin inflammation ate the site of application

  • Itching of the skin

  • Pain at the site of application

 

Up to 1 in 100 people may experience the following uncommon side effects:

  • Folliculitis

  • Rash

  • Red, itcy, scaly rash

  • Formation of blisters which may weep or become crusty

  • Dry skin

  • Changes in skin colour at the site of application

 

Rarely (up to 1 in 1000 cases), the following side effects may be experienced:

  • Hypersensitivity (allergic reaction)

  • Hypercalcaemia (excess calcium in the blood)

  • Temporary increased sensitivity to sunlight

  • Skin swelling or puffiness (oedema)

  • Itchy raised rash (hives)

  • Seborrhoeic dermatitis, such as dandruff or cradle cap

  • Hypercalciuria (excess calcium in the urine)

 

If any of the side effects listed above are troubling you, speak to your doctor for advice. They may choose to prescribe an alternative treatment for your Psoriasis. 

Contraindications

Do NOT use Dovonex if:

  • You are allergic to calcipotriol or any of the other ingredients in this medication

  • You have been told by a doctor that your have high or low levels of calcium in your body

  • You have severe liver problems

  • You have severe kidney problems

 

Dovonex should not be applied to the face, or used to treat Psoriasis in children under the age of 6.

 

Before using Dovonex, inform your doctor and take particular care if any of the following apply to you:

  • You are having ultraviolet (UV) light treatment

  • You have guttate, erythrodermic, exfoliative or pustular psoriasis (your doctor will be able to clarify this if you are unsure)

  • You are experiencing signs of excess calcium in the blood or urine. Signs include an increased need to pass urine, increased thirst, dry or metallic taste in the mouth, stomach pain, nausea, vomiting or constipation, weakness, muscle or bone pain, tired, fatigue or confusion.

Drug Interactions

Before using Dovonex, tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal supplements, and medicines purchased over the counter without a prescription. 

Treatment Options

Dovonex vs. Calcipotriol

Dovonex is a brand name of the generic drug Calcipotriol. Both contain the active ingredient Calcipotriol and work in the same way. 

Dovonex cream vs. ointment

Dovonex comes in the form of an ointment and a cream, both produced by LEO Pharmacy Inc. They work in very similar ways in the treatment of Psoriasis, but only the ointment is available in the UK.

Dovonex vs other Psoriasis Treatments

While Psoriasis cannot be cured, there are a range of treatments available which can dramatically reduce symptoms and outbreaks. These include topical treatments, systemic treatments and phototherapy, and the type of treatment recommended for you depends on your age, medical history and the severity of your condition. For mild cases of Psoriasis, over-the-counter emollient and moisturisers may be sufficient in reducing inflammation and scabbing. If your condition requires prescription treatment, your doctor will prescribe from a choice of Vitamin D analogues, such as Dovonex, and corticosteroids, which can be sued separately or in combination. Topical corticosteroids vary in strength, but in general should only be used sparingly as overuse can lead to skin thinning.

 

Should the above treatments prove ineffective, a doctor may chose to prescribe a calcineurin inhibitor, which work by reducing the activity of the immune system relieving inflammation. Common side effects of calcineurin inhibitory include skin irritation, burning or itching, but these tend to go away within a week. If your skin fails to tolerate other treatments, a doctor may choose to prescribe Dithranol, which works by suppressing the production of skin cells, or coal tar, which is effective in reducing scaliness, inflammation and itching. These treatments have less side effects than others, but care should be taken with Dithranol, which can cause burning if too concentrated. 

 

Systemic treatments are used in more severe cases of Psoriasis, or where topical treatments have failed to have an affect. These are tablets, capsules and injections which, while generally very effective, can have potentially serious side effects. Non-biological system treatments include Methotrexate and Acitretin, which both work by slowing the production of skin cells, and Ciclosporin, an immunosuppressant that is commonly used to prevent rejection during transplants. Neither Methotrexate Acitretin nor should not be used by pregnant women, or used in combination with alcohol. Acitretin carries a higher risk of side effects, including dryness and cracking of the mouth and nasal passage and hepatitis, and is generally only prescribed as a last resort. Ciclosporin can increase the risk of kidney disease and high blood pressure, which will need to be monitored throughout treatment. The most common biological systemic treatments are anti-TNF medications, such as Etanercept, Adalimumab, Infliximab and Ustekinumab. These treatments need to be injected, and you should take care to speak to your doctor about potential risks and benefits before use. 

 

Finally, long-term sufferers of Psoriasis may wish to try a form of phototherapy to slow down the excessive production of skin cells. There are 3 different types of phototherapy: ultraviolet (UVB) therapy, psoralen plus ultraviolet A (PUVA), and combination light therapy. Treatment takes place over a series of regular sessions in a hospital or dermatological clinic.

Dietary and lifestyle changes to help with Psoriasis

The direct cause of Psoriasis is unknown, but there are some changes you can make to your lifestyle to help reduce its impact on your daily life. First of all, try to work out what your triggers are; outbreaks of Psoriasis can be triggered by a number of factors, including stress, smoking, drinking too much, minor injuries, streptococcal infection, certain medications and disorders of the immune system. Identifying your triggers can help you to avoid or anticipate outbreaks. Whatsmore, taking care of yourself mentally and physically can reduce the severity of Psoriasis. Try to maintain a balanced and healthy diet and exercise regularly, which alongside boosting your physical fitness, can help to reduce the impact of stress in your day to day life. Having a BMI (body mass index) or being obese increases your chances of suffering from Psoriasis, so it is well worth making an effort to lose weight healthily and safely if necessary.

 

To improve the long-term health of your skin, you may wish to make some changes to your diet. Increase your nutritional intake of vitamin D by eating more oily fish, milk, yoghurt ad eggs, or try taking daily vitamin D supplements. Similarly, anti-inflammatory foods and antioxidants, such as oily fish, fruits and vegetables, nuts, seeds, legumes, fibre, and certain spices and herbs can reduce inflammation of the skin and improve its overall health over a few months. 

 

If receiving treatment for your Psoriasis, make sure to follow it strictly, and check in with your doctor regularly to discuss any concerns. 

Q&A

How effective is Dovonex?

Dovonex 50 microgram ointment is considered to be a safe an effective treatment for the long-term treatment of Psoriasis.

Can I use Dovonex with other skin products?

Dovonex can be used in combination with other skin products, but you should speak to a doctor if you are unsure about a particular product. If you are using any other topical medicines, including those purchased over the counter without a prescription, you should inform your doctor before using Dovonex. It is a good idea to moisturise regularly if you suffer from Psoriasis, particularly after washing. In this case, make sure moisturiser has been completely absorbed before applying Dovonex.

Can I use Dovonex on my face?

Dovonex ointment should not be applied to the face. If you are experiencing Psoriasis on your face, speak to your doctor about treatment options.

Dovonex and pregnancy

If you are pregnant or breastfeeding, think you might be pregnant or are planning on becoming pregnant, speak to your doctor for advice before using Dovonex. If your doctor agrees that you can breastfeed while using this medication, do not apply it to the breast area. 

Can I drink alcohol while using Dovonex?

You can drink alcohol while using Dovonex. However, you should be aware that drinking a lot of alcohol can cause symptoms of Psoriasis to worsen, as alcohol dehydrates the skin. 

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