Order doxycycline online to stay safe from malaria

  • An affordable but effective anti-malarial
  • Malarial prevention is very important, as infections can develop rapidly
  • Available from £17.99 + prescription fees and delivery costs

Our prices

Strength Quantity Price Stock
100mg37 capsules£17.99Out of Stock
100mg44 capsules£19.99Out of Stock
100mg51 capsules£21.99Out of Stock
100mg58 capsules£23.99Out of Stock
100mg65 capsules£25.99Out of Stock
100mg72 capsules£27.99Out of Stock
100mg86 capsules£31.99Out of Stock
100mg114 capsules£39.99Out of Stock
100mg212 capsules£59.99Out of Stock
100mg400 capsules£99.99Out of Stock
Prices exclude a prescription fee. This treatment requires a quick online consultation,
which a doctor will review to determine if a prescription is appropriate.

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Virginia Chachati

Reviewed by Virginia Chachati MPharm
(2013, University College London)
GPhC Registration number: 2087654

Information last reviewed 31/01/21


What is doxycycline?

Doxycycline is an antibiotic, but it is also an antimalarial to prevent malaria when travelling abroad.

How does doxycycline work?

Malaria is a parasitic infection. Doxycycline prevents the parasites from invading your red blood cells giving your immune system more time to fight off the parasites. Doxycycline does not prevent the initial infection, but it does prevent the development of the disease if you are infected.

How long does doxycycline take to work?

It can take two days for doxycycline to protect you against malaria. For this reason, you should start taking doxycycline two days before you are due to arrive in the malaria zone. 

Doxycycline summary


2 capsules the first day, then 1 capsule once per day after

Type of medicine

Antimalarial and tetracycline antibiotic 


Inhibits protein synthesis; prevents bacteria from reproducing

Available Size

37, 44, 51, 58, 65, 72, 86, 114, 212 or 400 capsules

Available Strengths


Active Ingredient

Doxycycline hyclate


From 25p per capsule

Side Effects

Can include sensitivity to sunlight, loss of appetite, nausea, vomiting, diarrhoea, rash and hives


Active ingredients

The active ingredient in doxycycline capsules is doxycycline hyclate.

Inactive ingredients

The inactive ingredients in doxycycline are sucrose, maise starch, crospovidone, basic butylated methacrylate copolymer (Eudragit E100) and purified talc.

Please note: inactive ingredients can vary between different brands of generic doxycycline. 


How to take doxycycline for malaria prevention

Always start taking doxycycline two days before you arrive in the malarial area. Take one capsule per day at around the same time each day. When you leave the affected area, continue to take one capsule per day for four weeks. 

When to start taking doxycycline for malaria prevention

You should start taking doxycycline two days before you travel to an area with malaria.

When to stop taking doxycycline for malaria

Continue to take one capsule of doxycycline per day for four weeks after leaving a malaria zone. Discuss with a doctor if you wish to stop taking doxycycline sooner due to side effects. 

What if I forget to take a dose?

If you forget a dose of doxycycline, take it as soon as you remember. Take your next dose at the usual time. Do not take a double dose to make up for a missed dose. If you miss a dose completely, seek medical advice and take additional precautions such as mosquito nets.

Side Effects

Doxycycline side effects

Like all medications, doxycycline can cause side effects in some patients. Common side effects include light-headedness, headaches, loss of appetite, nausea/vomiting, sensitivity to light, rash, shortness of breath and an increased heart rate. Please see the patient information leaflet for a full list of side effects.

You should also be aware that in rare cases, doxycycline can cause more serious side effects. Seek emergency medical attention if you experience a severe headache, changes to your vision, ringing in your ears, severe skin reactions, a severe allergic reaction affecting your breathing or fever with a rash and swollen lymph nodes.

How long do doxycycline side effects last?

You may experience side effects whilst taking doxycycline. Most side effects should resolve within a few days of stopping the medication. You should avoid exposure to strong sunlight or UV light for approximately 2 weeks after taking doxycycline. 

How to cope with doxycycline side effects

If you experience headaches, you could take ibuprofen or paracetamol to relieve the pain. Taking doxycycline with a meal can help to prevent nausea and vomiting. 

Doxycycline can increase your sensitivity to sunlight. Therefore, you should avoid strong sunlight, keep your skin covered and apply sunscreen. 


Do not take doxycycline if you have previously experienced an allergic reaction to doxycycline or any of its ingredients. You should avoid doxycycline if you are pregnant, breastfeeding or intending to become pregnant. Your doctor should be able to recommend a suitable alternative. 

Always inform the prescribing doctor of any pre-existing medical conditions. Doxycycline may not be suitable for you if you have certain liver or kidney problems, myasthenia gravis, porphyria or systemic lupus erythematosus. 

If you usually experience diarrhoea in response to antibiotics, an alternative antimalarial may be more suitable. Lastly, doxycycline can increase your sensitivity to sunlight. Therefore, it could be less suitable if you are going to be exposed to strong sunlight during your travels. 

Drug interactions

Some medications can interact with doxycycline. Always inform the prescribing doctor of all medications you are currently taking, including over the counter treatments and herbal remedies. Medications with a known interaction include some antacids, antibiotics, anticoagulants (warfarin), and anti-epileptic drugs amongst others. 

Please see the patient information leaflet for a full list of doxycycline drug interactions.

Can you drink alcohol when taking doxycycline?

Alcohol can reduce the effectiveness of doxycycline, therefore you should not drink alcohol while taking doxycycline.

Doxycycline and pregnancy

Do not take doxycycline if you are pregnant, planning to become pregnant, or breastfeeding. Doxycycline can affect your baby’s development, but your doctor will be able to recommend more suitable treatments. 


Do I need to buy doxycycline before I travel?

You will need to start taking doxycycline two days before you travel to a malaria zone. Therefore, you should buy your doxycycline before travelling. If you need to buy more doxycycline whilst you are away, ensure you buy from a reputable and reliable source. 

How long does sun sensitivity last after doxycycline?

Sensitivity to sunlight and UV light typically resolves within 10-14 days of stopping doxycycline. During this time you should avoid exposure to strong sunlight, wear sunscreen and cover your skin when possible.

Will doxycycline give me thrush?

Doxycycline is a broad-spectrum antibiotic and may suppress some helpful bacteria that naturally reside in the body. This can lead to an overgrowth of yeast that can cause thrush. For this reason, doxycycline can lead to an outbreak of thrush in some patients.

Will doxycycline stain my teeth?

Doxycycline can stain the teeth, but this is most likely to happen during periods of tooth development. For this reason, it is usually not recommended for children under 8 years old. If discolouration does occur, it may be possible to remove the stains with dental treatments.

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