Reviewed by Virginia Chachati MPharm
(2013, University College London)
GPhC Registration number: 2087654
Information last reviewed 08/02/21
Dymista nasal spray is a combined steroid and antihistamine treatment for hayfever and nasal allergies.
Dymista contains azelastine hydrochloride, an antihistamine, and fluticasone propionate, a corticosteroid. Azelastine reduces histamine release to prevent an allergic reaction being triggered by pollen. Fluticasone reduces inflammation in your nose. Together, azelastine and fluticasone help treat and prevent symptoms such as a runny nose, nasal congestion, sneezing and itchy or watery eyes caused by hay fever or other nasal allergies.
Dymista is most effective when it’s used twice a day, every day for as long as it’s needed. The azelastine component of Dymista provides instant relief while the fluticasone component works in the background to prevent symptoms from occurring.
Dymista works quickly within 30 minutes after using it. However, Dymista needs to be used daily as it takes a few days to achieve the best prevention and treatment of your symptoms.
Dose |
One spray into each nostril, twice a day (morning and evening) |
Type of Medicine | Antihistamine and corticosteroid nasal spray |
Mechanism |
Azelastine is a H1-receptor antagonist, blocking histamine reactions that cause allergy symptoms Fluticasone is a synthetic corticosteroid, that binds receptors to producer an anti-inflammatory effect, reduce swelling and tenderness |
Available Size |
23g spray |
Available Strengths |
137mcg azelastine hydrochloride/50mcg fluticasone propionate |
Active Ingredient |
Fluticasone propionate, azelastine hydrochloride |
Price |
From £24.43 per spray |
Side Effects |
Can include nosebleed, headache, bitter taste, unpleasant smell, irritation of the inside of the nose, dry mouth |
The active ingredients in Dymista nasal spray are azelastine hydrochloride and fluticasone propionate.
The inactive ingredients in Dymista nasal spray are disodium edetate, glycerol, microcrystalline cellulose, carmellose sodium, polysorbate 80, benzalkonium chloride, phenylethyl alcohol and purified water.
For adults and children over 12 years old, the typical starting dose is one spray in each nostril twice a day.
Before using Dymista nasal spray, shake the bottle for five seconds. If it’s the first time you’ve used Dymista, you’ll need to prime the pump by pressing down six times until it releases a fine mist into the air. When ready, blow your nose into a clean tissue and wash your hands. Look downwards, release a spray into your nostril, breathing in gently at the same time. Breathe out slowly through your mouth and repeat the process for your other nostril. Avoid tilting your head backwards as this can cause the medicine to collect in the back of the throat.
Common side effects you may experience while using Dymista include:
Less common side effects include:
In rare cases you may experience:
If you are allergic to azelastine, fluticasone or any of the other ingredients then do not use Dymista. Tell your doctor if:
You should let your doctor know if you are taking any other medicines or herbal remedies. These include:
Other types of nasal sprays should not be used alongside Dymista without your doctor’s recommendation.
You should avoid drinking alcohol while using Dymista as you are more likely to develop side effects.
You should speak to your doctor if you are pregnant, planning a pregnancy or breastfeeding before using Dymista.
If Dymista makes you feel drowsy or sleepy, then do not drive while using it.
Dymista should not be used alongside any other nasal spray or steroid treatment. Hay fever treatments such as eye drops or tablets can be used alongside Dymista, but you should always check with your doctor to make sure they do not interact with Dymista or cause side effects.
Dymista prevents and relieves the symptoms of hay fever. In Dymista there are two components that work together to do this. These are Azelastine, a fast-acting antihistamine, and fluticasone, an effective long-lasting anti-inflammatory.
Dymista can be used long term, under the guidance of your doctor. You can use Dymista seasonally, for example when you will be exposed to allergens such as pollen, dust mites or pet hair for long periods of time.
Dymista is used for allergies that affect the nasal area. This could be hay fever, pet hair or dust mites. Your doctor may recommend that you use Dymista for other allergies if necessary.
Dymista contains two active ingredients; one is an antihistamine (azelastine) and one is a steroid (fluticasone). Fluticasone is a type of steroid known as a corticosteroid.
Dymista is safe to use as directed by your doctor. Dymista is not recommended for children under the age of 12 years old.
Dymista is not available over the counter. You need a prescription from a doctor, such as Dr Felix, to get Dymista.
Dymista is not addictive. When you no longer need to use Dymista, your doctor will guide you on how to gradually reduce the dose so you can stop using it.
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