Order Fexofenadine to relieve hay fever symptoms

Fexofenadine is an antihistamine that comes in tablet form and helps treat allergies including hay fever, allergic conjunctivitis, eczema and insect bites or stings.

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Strength Quantity Price Stock
120mg30 tablets£12.99In Stock
120mg60 tablets£22.99In Stock
120mg90 tablets£30.99In Stock
180mg30 tablets£13.99In Stock
180mg60 tablets£24.99In Stock
180mg90 tablets£32.99In Stock
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Virginia Chachati

Reviewed by Virginia Chachati MPharm
(2013, University College London)
GPhC Registration number: 2087654

Information last reviewed 28/02/21


What is Fexofenadine?

Fexofenadine is an antihistamine that comes in tablet form. It’s used to treat a number of allergies including hay fever, conjunctivitis, eczema and insect bites or stings. 

How does Fexofenadine work?

Fexofenadine blocks histamine receptors to prevent histamine from causing an allergic reaction. Histamine is a chemical that you naturally produce in response to the presence of an allergen, such as pollen; it's what causes the symptoms of an allergic reaction to occur, setting off a chain reaction within the body. Fexofenadine stops these symptoms from getting worse or occurring in the first place.

How long does Fexofenadine take to work?

Fexofenadine will start to work within one or two hours.

How effective is Fexofenadine?

Fexofenadine is a prescription only medicine and can be more effective than over the counter treatments you can buy from a pharmacy.


Active ingredients

Fexofenadine hydrochloride is the active ingredient in Fexofenadine tablets.

Inactive ingredients

The inactive ingredients in Fexofenadine tablets are: powdered cellulose, mannitol (E421), maize starch, croscarmellose sodium, colloidal anhydrous silica, magnesium stearate.
Tablet coating: opadry pink film-coating mixture containing hypromellose (E464), titanium dioxide (E171), macrogol 400, allura red AC lake (FD&C Red #40) (E129), and iron oxide, black (E172).

Please Note: Different generic brands of Fexofenadine may contain different inactive ingredients. Please read the patient information leaflet provided for further details

Which ingredients can cause an allergic reaction?

Lessina contains FD&C red no. 40 aluminum lake which has been linked to some cases of allergic reactions or hypersensitivity reactions. It is rare for Fexofenadine to cause a severe allergic reaction resulting in hives/rash, facial swelling, dizziness, and difficulty breathing. If you notice any of these symptoms please get immediate medical attention after taking Fexofenadine.


How to take Fexofenadine?

Always take Fexofenadine as prescribed by your doctor. Fexofenadine is typically taken once a day. A Fexofenadine tablet should be swallowed whole with water before food.

Fexofenadine dosage

Fexofenadine comes in three strengths; 30 mg, 120 mg or 180 mg. Adults and children over 12 years old can take either 120 mg or 180 mg once a day. Children between 6 years old and 11 years old typically take 30 mg twice a day. Fexofenadine is not recommended for children under 6 years old.

Can Fexofenadine be crushed or split?

Fexofenadine tablets should be swallowed whole. Do not split or crush Fexofenadine  tablets unless it specifies on the packet that it's suitable to do so. Crushing or splitting a Fexofenadine tablet can affect how it is absorbed by the body, and it may not work as expected.

Is Fexofenadine the strongest antihistamine?

Fexofenadine is a prescription only medicine and its effects can last longer than other antihistamines which may be available over the counter at a pharmacy. In general, the medicine and dose you are prescribed will be specific to your allergy, the severity of it and the symptoms you experience. 

Side Effects

Fexofenadine side effects

Common side effects which may occur after taking Fexofenadine include: 

  • Nausea
  • Drowsiness
  • Headaches
  • Dizziness
  • Dry mouth 

If your heart rate increases or you experience heart palpitations after taking it then seek emergency medical attention. 

The signs of an allergic reaction include: 

  • Difficulty breathing
  • A tight chest
  • A rash
  • Swollen tongue, face or neck
  • Wheezing 

If you experience an allergic reaction to Fexofenadine, seek emergency medical attention immediately.


Fexofenadine may not be suitable if:

  • You are over 65 years old
  • You are allergic to Fexofenadine or any other medicine
  • You have liver or kidney problems 
  • You have a history of heart problems 
  • You have epilepsy 
  • You are due to have an allergy test

Let your doctor know if any of these circumstances apply.

Drug interactions

The following medicines may interact with Fexofenadine: 

  • Midodrine
  • Ketoconazole
  • Erythromycin 
  • Certain types of HIV medicines
  • Rifampicin
  • Indigestion medicines containing aluminium 
  • Any medicines which can cause drowsiness

How to cope with Fexofenadine side effects?

If Fexofenadine makes you feel sick then avoid high fat, oily or spicy foods until you feel better. Drink plenty of water or consider taking a painkiller if you get a headache. While Fexofenadine is classed as a non-drowsy antihistamine, it can cause drowsiness in some people. If this continues then you should speak to your doctor to switch to an alternative antihistamine. 

Fexofenadine and alcohol

Drinking alcohol should be avoided while taking Fexofenadine as it can make you feel sleepy.

Fexofenadine and driving

When you start taking Fexofenadine you should wait to see how it affects you before you drive. Fexofenadine can cause drowsiness in some people and in this case you should not drive

Will Fexofenadine affect my contraception?

Both hormonal and non-hormonal types of contraception are not affected by Fexofenadine. 

Will Fexofenadine affect my fertility?

Fexofenadine is not known to affect fertility in either men or women.

Does Fexofenadine make you drowsy?

Fexofenadine is a non-drowsy antihistamine. This means it's less likely to make you feel drowsy in comparison to other hay fever treatments. However, Fexofenadine can make some people drowsy or sleepy as a side effect, although it is uncommon.

Treatment Options

Lifestyle changes that can help hay fever

There are lifestyle changes you can make to reduce your hay fever symptoms. These include spending less time outdoors when the pollen count is high, closing your windows at home and not keeping fresh flowers in the house. When outdoors, wear wraparound sunglasses and avoid walking over freshly cut grass to avoid contact with pollen that can trigger your hay fever symptoms. Smoking can also make hay fever feel worse, so you may want to cut down or quit.


Can I take Fexofenadine with other hay fever treatments?

Fexofenadine can be used alongside other hay fever treatments such as eye drops or nasal sprays. You should not take Fexofenadine with other oral antihistamines. Always check with your doctor before taking multiple medicines at the same time.

Can Fexofenadine be used for other allergies?

Yes, Fexofenadine can be used to treat eczema, hives, insect bites or stings, allergic conjunctivitis and certain types of food allergies.

Is Fexofenadine safe for long term use?

You should only use Fexofenadine as prescribed by your doctor. Fexofenadine is unlikely to cause any harm if it's used for a long period of time. Depending on the nature of your allergy, you may only need to use it for a short time.

Why is Fexofenadine only available on prescription?

Fexofenadine is a more potent antihistamine than those available over the counter at a pharmacy. For this reason, it is only available on prescription if your doctor thinks it will help you.

Why is Fexofenadine only available on prescription?

Fexofenadine is a stronger type of medication than most antihistamines which is why it is not available over the counter. 

Is Fexofenadine banned in Qatar?

Carrying medicines and controlled substances when travelling to Qatar is highly regulated. You may need to apply electronically for permission to take your medicines with your prior to travel. For certain medicines, this does not apply but you will still need to ensure you bring the prescription with you and any other relevant documents.

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