Fluconazole is an oral medication that is used to treat yeast infections, commonly known as thrush, caused by the candida fungus. Fluconazole is used to treat a variety of fungal infections, including vaginal, penile and oral thrush.
Fluconazole is an antifungal medicine that works by stopping candida yeasts from building new cells. So it essentially stops the candida yeast from being able to multiply and maintain itself in such high numbers. This leads to an overall reduction in the number of yeast cells, and in most cases, complete elimination of the troublesome symptoms.
A single 150mg dose of fluconazole will usually clear up 80–95% of yeast infections. However, it may not work for everyone, so if your symptoms persist or come back soon after being treated, your doctor might need to prescribe additional treatment.
One capsule, taken once. If symptoms clear up but return within 7 days, you may take another.
|Type of Medicine||Triazole antifungal|
Prevents synthesis of fungal cell walls, meaning no new fungal cells can be formed
1 or 2 capsules
From £4.08 per capsule
Can include headache, stomach discomfort, diarrhoea, nausea
The active ingredient in this medication is 150mg of fluconazole.
The other ingredients include: lactose monohydrate, microcrystalline cellulose, pregelatinised maize starch, sodium lauryl sulfate, colloidal anhydrous silica, magnesium stearate, titanium dioxide (E171), quinoline yellow (E104), sunset yellow (E110), gelatin
Please note: different brands of fluconazole may contain different inactive ingredients.
This medication contains lactose monohydrate. If you have a severe lactose allergy or a deficiency that affects your lactose metabolism, you might experience some uncomfortable gastrointestinal symptoms after taking this medication. It is, however, safe for people with mild lactose intolerance as they are present in small amounts. On the other hand, a severe allergic reaction to this medication is rare. Get medical help if you notice hives, swelling of the face, dizziness, chest tightness, and shortness of breath.
Fluconazole is normally taken as a one-off 150mg capsule which should be swallowed whole with a glass of water. It can be taken at any time of the day, with or without food.
The first line dosage of fluconazole for uncomplicated thrush is typically a single 150mg capsule, however, the dose you are given will depend on what type of infection you are being treated for. Always take the amount specified by your doctor.
Fluconazole 150mg is designed to be taken as a one-off dose. If your symptoms clear up but return within 7 days, you may take another capsule. Fluconazole is not designed to be taken on a regular basis, you should contact your doctor if you have persistent symptoms.
Fluconazole should be swallowed whole with a glass of water. It should not be crushed or split. If you think you’ll struggle to swallow it, consult your prescriber for advice.
Common side effects: affect up to 1 in 10 people
Less common side effects: affect up to 1 in 100 people
Rare side effects: affect up to 1 in 1,000 people
You shouldn't take fluconazole if you:
Consult your doctor if you:
There are certain types of medication that can interact with fluconazole. These include:
There are many medications that may potentially interact with antifungal medication, so it’s important to disclose all of your regular and recent medication to your prescriber.
Extra care should be taken if you are taking any of the following:
You should not use fluconazole during pregnancy unless your doctor has specified that it is safe.
Fluconazole does not impact either your contraception or your fertility.
If you experience any side effects of fluconazole, you should speak with your doctor. Most side effects will disappear within 4–5 days.
Fluconazole will usually start to work after three days and you can expect your symptoms to clear up within seven days. If this doesn't happen, you may need to see your doctor so they can assess your symptoms and rule out other conditions that may be causing them. Aspects of your lifestyle can also leave you prone to yeast infections. Simple tips such as wearing loose-fitting underwear, avoiding perfumed products on your genitals, and keeping blood sugar levels in check can all help to reduce the risk of recurrence.
Fluconazole is an oral antifungal. There are other versions of this type of medication available e.g. itraconazole.
If an oral capsule is not suitable for you, you might wish to use an intravaginal cream or pessary. These are shown to be just as effective for vulvovaginal thrush.
Canesten is a brand name of several different products used to treat thrush. Canesten manufactures a 500mg clotrimazole intravaginal pessary, and 10% clotrimazole intravaginal cream 2% clotrimazole cream. Canesten also manufactures handy “combi” packs which include both a pessary or intravaginal cream, and a topical cream to treat both external vulval infection and internal vaginal infection. Intravaginal pessaries or gels are shown to have similar results to oral fluconazole when treating the symptoms of thrush.
Fluconazole is available to buy over the counter from certain pharmacies, Canesten is the most readily available type of fluconazole to purchase.
Symptoms should start to subside within three days of taking fluconazole. If your symptoms persist after a week, you should speak with your doctor.
It will vary depending on your liver and kidney function, but fluconazole may stay in your system for up to 7 days.
No, fluconazole is an antifungal treatment, it works to inhibit fungal growth.
Oral fluconazole is not a first-line treatment for athlete's foot. Athlete’s foot is caused by a different type of fungus. Mild cases of athlete's foot respond well to specific topical therapies such as terbinafine cream. More severe cases do require oral therapy, however, fluconazole is not routinely used. If you have athlete's foot, it is recommended that you use a treatment designed for athlete's foot. You should not use medications for conditions that they were not prescribed for unless you have discussed this with your doctor.
Fungal nail infections are generally treated with topical therapies. If you have got a fungal nail infection, you should use a treatment designed for this. You should not use treatments that have been prescribed for other purposes without first checking this with your doctor.
Fluconazole is not a steroid, it is an antifungal treatment.
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