Reviewed by Dr Samantha Miller MB ChB
(2017, University of Glasgow)
GMC number: 7561464
Information last reviewed 05/09/2021
Lipitor is a type of lipid-regulating medicine containing the active ingredient atorvastatin. Statins such as atorvastatin work in combination with a healthy lifestyle and diet to lower cholesterol in patients at high risk of heart attack or stroke.
The liver produces a substance called cholesterol, which is vital for the functioning of all cells in the body. While a high level of high-density lipoprotein (HDL), or “good” cholesterol, in the blood is healthy, a high level of low-density lipoprotein (LDL), the “bad” cholesterol, can build up in your arteries and lead to a heart attack or stroke. Maintaining a healthy lifestyle, including eating a balanced diet that is low in saturated fat, and exercising regularly, is the best way to reduce levels of LDL in the blood. In addition, Lipitor works by reducing the amount of LDL produced by the liver and is prescribed to patients at high risk of heart attack or stroke.
Lipitor is most effective when taken long-term with the appropriate lifestyle changes. If taken correctly, your cholesterol levels should begin to drop noticeably within four weeks.
Statins such as Lipitor are usually taken for life, as the benefits wear off once treatment ends. They are usually only prescribed to patients at high risk of developing heart disease, such as those with a history of stroke or heart attack. The benefits of statins increase over time, and coming off them suddenly can be very dangerous. Never stop taking statins without first consulting a doctor.
Dose |
Normally one tablet once per day |
Type of Medicine |
Statin |
Mechanism |
Inhibits the production of the enzyme responsible for creating cholesterol |
Available Size |
84 tablets |
Available Strengths |
10mg, 20mg or 40mg |
Active Ingredient |
Atorvastatin calcium |
Price |
From 70p per tablet |
Side Effects |
Can include dizziness, flatulence, sleep disorders, nausea, vomiting, constipation or diarrhoea, abdominal discomfort, nosebleeds, hypersensitivity |
The active ingredient in Lipitor is atorvastatin calcium.
The inactive ingredients in Lipitor are lactose, cellulose (E460), magnesium oxide, magnesium stearate (E470b), crospovidone, (E1202), hypromellose (E464), triacetin (E1518), titanium dioxide (E171), lactose monohydrate and iron oxide yellow (E172).
Note :different doses or formulations may contain different inactive ingredients
Always take Lipitor as instructed by a doctor. Lipitor tablets should be swallowed whole with a drink of water and can be taken at any time of day, with or without food. Before starting this medication, your doctor will start you on a low-fat diet. To help you remember, try and make this a part of your daily routine - for example, take your tablet when you brush your teeth in the morning.
If you forget to take a tablet, just skip the dose and take your next tablet at the scheduled time. Never take a double dose to make up for a missed one.
Lipitor can be purchased as 10 mg, 20 mg or 40 mg tablets, to be taken once daily as instructed by a doctor.
If you experience either of the following, stop taking this medication and consult a doctor immediately:
Common or very common side effects (occur in up to 1 in 10 people)
Uncommon
Rare or very rare
Frequency not known
Like all medications, Lipitor can cause side effects in some patients. Your doctor will usually prescribe a low dose to start with and gradually increase it at intervals of at least four weeks if necessary. If you experience troublesome side effects, consult your doctor about the possibility of switching to a different statin or high-cholesterol medication. Most side effects are mild, the most common being muscle pain or cramps. To relieve cramps, try doing daily stretching exercises and wearing compression stockings. Avoid wearing high-heeled shoes and keep your arms and leg muscles warm. Your doctor may also recommend taking magnesium supplements.
Do NOT take Lipitor if you:
Before taking Lipitor, tell your doctor and take special care if you have:
Before starting Lipitor, tell your doctor if you are taking any other medications, including those bought over the counter without a prescription. In particular, tell your doctor if you are taking any medications for your immune system, cholesterol, infections, birth control, heart failure, HIV or AIDS.
While taking Lipitor, avoid drinking too much grapefruit juice, as it can increase the concentration of this medication in your system. Drink no more than two small glasses per day, and never within an hour of taking your medication.
You can drink alcohol while taking this medication, but you are advised not to drink more than the recommended 14 units per week. Too much alcohol can increase the effectiveness of Lipitor, which can be dangerous.
Do not take Lipitor if you are pregnant, think you might be pregnant, are planning on becoming pregnant, or are breastfeeding.
Most people can drive while taking Lipitor. If you feel dizzy or tired after taking Lipitor, you should not drive whilst taking this medication.
The best way to reduce cholesterol levels is to make changes to your lifestyle, and before prescribing statins your doctor will place you on a low-cholesterol diet. Cut down on foods that are high in saturated fats, such as fatty or processed meats, butter and lard, cream and ice cream, cheese (particularly hard cheese) cakes, biscuits, chocolate, and products containing coconut or palm oil. Exercising regularly is imperative, as is losing weight healthily if you are overweight. You should also try to cut down on alcohol and caffeine and, if you haven’t already done so, quit smoking.
The five types of statins available on prescription in the UK are atorvastatin (Lipitor), fluvastatin (Lescol), pravastatin (Lipostat), rosuvastatin (Crestor) and simvastatin (Zocor). The main difference between them is the degree to which they lower your cholesterol levels. Low-intensity statins such as fluvastatin, pravastatin and simvastatin are sufficient for lowering cholesterol in the majority of patients. If a doctor feels you are at higher risk, or that a higher dosage is needed, they may prescribe a high-intensity statin such as atorvastatin or rosuvastatin. Different statins can have different side effects and may affect people in different ways. If you are worried about troublesome side effects, your doctor may choose to prescribe you a different type of statin.
Lipitor is not a cure for high cholesterol, and blood cholesterol levels will rise again if this medication is stopped. For this reason, Lipitor is usually taken for life and, when used in combination with the correct lifestyle changes, is an effective means of lowering cholesterol and reducing the risk of heart disease.
You will not be able to feel Lipitor working, but your doctor may wish to conduct regular blood tests to monitor your blood cholesterol levels. If you maintain a healthy diet and lifestyle, Lipitor will work to its full potential.
High-density lipoproteins (“good cholesterol”) are beneficial to the body, while low-density proteins (“bad cholesterol”) can be dangerous. High levels of “bad cholesterol” can lead to a heart attack or stroke and it is therefore essential to reduce levels if high.
Prices from:
Low to moderate intensity statin
Moderate to high intensity statin
Low to moderate intensity statin
Low to moderate intensity statin
Moderate to high intensity statin
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