Order Loestrin to enjoy sex without fear of pregnancy

  • Loestrin has been discontinued by the manufacturer so is no longer available. Dr Felix offers a range of other contraceptive pills.

  • Combined contraceptive pill that contains both oestrogen and progestogen.

  • Designed to prevent pregnancy, but may also be prescribed for irregular periods or to reduce period pains

Our prices

Strength Quantity Price Stock
20mcg/1mg63 tablets£13.95Out of Stock
30mcg/1.5mg63 tablets£13.95Out of Stock
Prices exclude a prescription fee. This treatment requires a quick online consultation,
which a doctor will review to determine if a prescription is appropriate.

Safe and discreet

  • Safe and regulated treatments
  • 100% discreet and confidential
  • UK qualified doctors
  • Fully registered UK pharmacy


Dr Samantha Miller

Reviewed by Dr Samantha Miller MB ChB
(2017, University of Glasgow)
GMC number: 7561464

Information last reviewed 23/02/2021


What is Loestrin?

Loestrin is a type of combined contraceptive pill. More commonly referred to as ‘the pill’, it is an effective and popular method of preventing pregnancy containing oestrogen and progestogen hormones.

Loestrin Summary


One pill, taken once per day, at the same time each day

Type of Medicine

Hormonal contraceptive


Prevents ovulation, thickens mucus to make it harder for sperm to reach eggs, and prevents egg attachment to the uterus

Available Size

63 tablets

Available Strengths

20mcg/1mg or 30mcg/1.5mg

Active Ingredient

Loestrin 20 - 1mg norethindrone acetate and 20 mcg ethinylestradiol

Loestrin 30 - 1.5mg norethindrone acetate and 30 mcg ethinylestradiol.


From 22p per tablet

Side Effects

Can include changes to your bleeding during your menstrual cycle, including spotting and breakthrough bleeding, headache, mood changes, breast tenderness

How does Loestrin work?

Loestrin contains ethinylestradiol and norethisterone which are synthetic versions of oestrogen and progestogen, similar to the hormones that the body naturally produces. These hormones work to prevent ovulation from happening so that an egg does not get released into the womb to be fertilised. They also create a thinner womb lining so that an egg would be unable to attach itself to the uterine wall. Furthermore, the mucus that lines the entrance of the womb from the vagina thickens, preventing sperm from being able to enter.

How effective is Loestrin?

When taken correctly, Loestrin is over 99% effective. Forgetting to take it is one of the main reasons the pill becomes less effective. It can also be affected by vomiting and diarrhea or certain medications. Always familiarise yourself with the instructions provided with Loestrin before starting it so that you are aware of how it works. Typically, this pill is around 91% effective in practice. 

When does Loestrin start to work?

Loestrin will start to work right away if you start taking it on the first day of your period. If you begin your first pack after this then you will need to use condoms for the first seven days until Loestrin takes effect.

Other purposes for Loestrin

While Loestrin is predominantly used to prevent pregnancy, it also provides some additional benefits. It can be used to delay your period, to ease painful periods, and to reduce the symptoms of PMS. The pill causes you to have an artificial menstrual cycle that is regular and easy to control.


Which ingredients can cause an allergic reaction?

You should not use Loestrin if you know you are allergic to one of its ingredients above. Loestrin birth control rarely causes a severe allergic reaction after consumption. Rash/hives, trouble breathing and swelling of the face are signs of a severe allergic reaction. Make sure to seek medical attention if you notice these symptoms.

Active ingredients

Each Loestrin 20 pill contains 1mg norethindrone acetate and 20 mcg ethinylestradiol.
Each Loestrin 30 pill contains 1.5mg norethindrone acetate and 30 mcg ethinylestradiol.

Inactive ingredients

The inactive ingredients in Loestrin are: acacia, lactose, magnesium stearate, starch, confectioner's sugar and talc.


What should I do if I missed a pill?

If you have missed a pill (i.e. you are more than 12 hours late in taking it) then your contraceptive cover may be affected. Take the missed pill as soon as possible, even if this means you are taking two on the same day. Continue with the rest of the pack as normal and use extra precautions for seven days. If you have missed two or more pills then your contraception is more likely to be affected. Take the most recent missed pill as soon as you can and continue taking the rest of your pack on time. You'll need to use condoms for the next seven days to ensure you don't fall pregnant. If you have had unprotected sex since you missed a pill then you may need emergency contraception. Seek advice from your doctor, pharmacist or sexual health clinic as soon as possible.

What should I do if I took a pill too late?

If you take your pill within 12 hours of your scheduled time then your protection against pregnancy won't be affected. If you are more than 12 hours late, follow the instructions for a missed pill.

How to start Loestrin

The best time to start Loestrin is on the first day of your period as you will be protected against pregnancy right away. If you start at any other time during your cycle, you'll need to use additional methods of contraception, such as condoms, for the first seven days. If you are switching from a different brand of combined pill, you should finish your current pack and begin taking Loestrin the next day. In this way, you will be protected from pregnancy right away.

How to take Loestrin

Loestrin should be taken once a day at the same time each day. Each pill pack contains a 21 day supply. You'll take the pill every day for 21 days and then have a seven-day break before starting the next pack.

Side Effects

How to cope with Loestrin side effects

It's common to experience side effects when you first start taking Loestrin but these should subside after the first couple of months. Drink plenty of water and take painkillers if you experience headaches or cramps. It's normal to have breakthrough bleeding in the first month so be prepared with tampons and sanitary pads to ensure you are comfortable. Practice self-care if you experience mood changes and be mindful of how you are feeling. If you are struggling with side effects after the first few months of taking Loestrin, speak with your doctor as there may be a better type of contraceptive for you.


The pill should not be taken if:

  • You are pregnant, or might be pregnant 
  • You smoke and are over the age of 35
  • You have, or have ever had, a blood clot
  • You have sickle cell anaemia
  • You have very high cholesterol or lipids in the blood
  • There is a history of blood clots in your family
  • You have ever had a stroke or mini-stroke
  • You have ever had a heart attack or suffer from angina
  • You have problems with your heart
  • You have very high blood pressure
  • You have ever experienced migraines with aura
  • You have, or have ever had, breast cancer or endometrial cancer
  • You have abnormal vaginal bleeding of unknown cause
  • You have had a condition that first appeared in pregnancy
  • You have jaundice
  • You have liver or gallbladder disease 
  • You are allergic to any of the ingredients

Loestrin side effects

There are some serious side effects associated with the pill which you should be aware of before taking it. The combined pill increases the risk of high blood pressure, blood clots and some cancers. These side effects are rare, however, and your doctor will assess your medical history and any underlying conditions to determine if the pill is suitable for you or not. 

Common side effects include: 

  • Headaches
  • Breakthrough bleeding or spotting between bleeds
  • Nausea and vomiting
  • Mood changes including depressive mood
  • Breast tenderness
  • Changes in body weight
  • Changes in libido (interest in sex)

Loestrin may cause worsening of the following conditions

  • Depressive states
  • Varicose veins
  • Diabetes
  • High blood pressure
  • Otosclerosis
  • Multiple sclerosis
  • Porphyria 
  • Liver disease
  • Gallbladder disease including gallstones
  • Cardiovascular disease
  • Chloasma 
  • Fibroid

Drug interactions

Certain medications interact with the way Loestrin works. These include: 

  • Rifampicin 
  • Rifabutin 
  • Carbamazepine 
  • Oxcarbazepine
  • Phenytoin 
  • Phenobarbital
  • Primidone
  • Topiramate
  • HIV treatments 
  • St John's Wort

Loestrin and alcohol

Drinking alcohol does not have an effect on Loestrin. 

Treatment Options

Loestrin vs the mini pill

Loestrin is not suitable for everyone. For women who cannot take the combined pill, the mini-pill may be a viable alternative. Also known as the progestogen-only pill, in contrast to Loestrin, it only contains the progestogen hormone. This means it produces fewer side effects and won't cause high blood pressure. It cannot be used to control your period in the same way as Loestrin and is taken every day throughout the month, rather than for 21 days.

Alternatives to Loestrin

Loestrin 20 has a lower dose of oestrogen than other brands of the combined pill making it a milder option that may suit some women better. Similar combined pills with a low-dose of oestrogen are Gedarel, Mercilon, Femodette, Millinette and Sunya.

If oestrogen is not suitable for you, you might consider a progestogen-only pill e.g. Cerelle.

Longer term alternatives to the pill include the copper coil, the hormonal coil, the contraceptive implant, injection or patch. None of these options will protect against STIs; male and female condoms are the only method of contraception that prevents a sexually transmitted infection. 

Switching contraceptive pill

When switching contraceptive pills you can usually start your new pill right away without any issues. However, it may depend on which type of pill you are switching from so ensure you follow your doctor's advice about how to start Loestrin. In most cases, when switching between brands of combined pills, you should finish your current pack and then start Loestrin the next day. As a precaution, you may be advised to use condoms for the first seven days of swapping pills.

Has Loestrin been discontinued?

Loestrin has been discontinued by the manufacturer, so it is no longer available through Dr Felix. There is no alternative pill that contains exactly the same hormones, however, there are various pills that contain the same dose (30mg) of oestrogen:

Alternatives to Loestrin 20 which also contain a lower 20 micrograms dose of oestrogen (20 micrograms ethinylestradiol) are:

Your doctor can help you identify which pill is best for you to take instead of Loestrin.


Can you use Loestrin for period delay?

One of the advantages of Loestrin is that it can be used to delay your period. The pill is usually taken for 21 days before having a seven-day break. To delay your period with Loestrin, run two packs back-to-back instead of having your usual pill-free week. This will skip your period until the end of your next pill pack.

If I have vomited, will Loestrin still work?

Vomiting or diarrhoea can cause Loestrin to become ineffective. In this case, try to continue your pills as normal, but use additional barrier contraception for the duration of your illness and for 7 days thereafter. If those seven days overrun the end of the pack, the next pack should be started without a break.

When can I get pregnant after taking Loestrin?

Some women may get pregnant as soon as they stop taking Loestrin but for others, it can take longer. When you come off the pill it can take a couple of months for your natural menstrual cycle to return as your body adjusts. Loestrin does not have a long-term effect on your fertility but there are many other factors to consider for a healthy conception such as a healthy diet and not smoking or drinking alcohol. 

Prices from:

Start your consultation now

We’re a fully regulated pharmacy, with qualified doctors and happy customers


Quick and discreet

Amazing service will definitely be using again!!


What is your gender?


Quick and discreet

Excellent service and exceptional delivery - will use again