Loperamide

Order Loperamide Hydrochloride 2mg tablets online

Loperamide capsules slows down the pace at which the gut processes food. This leads to more water being absorbed and firmer stools.

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Loperamide Brand Names: Imodium® or Imodium® Instants, Norimode®, Normaloe®, Diocalm® and Entrocalm®.

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2mg30 capsules7.99
2mg60 capsules13.99
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About

What is Loperamide?

Loperamide is a treatment for diarrhoea and works as a quick relief to settle loose stools. It can be used to ease a temporary bout of diarrhoea or to help treat the symptoms of long term conditions like irritable bowel syndrome (IBS), Crohn's disease or ulcerative colitis. 

How does Loperamide work?

Loperamide works by slowing down the rate in which food travels through the bowel to give it time to absorb water, resulting in firmer stools (poos). 

How long does Loperamide take to work?

Loperamide should start to work within an hour.

Ingredients

Active ingredients

The active ingredient is loperamide hydrochloride.

Inactive ingredients

The other ingredients are lactose monohydrate, maize starch and magnesium stearate.

Please Note: Different generic brands of Loperamide may contain different inactive ingredients than those stated here.

Dosage

How to take Loperamide

Take two Loperamide capsules to begin with and then one after every loose stool. The tablets should be swallowed whole with plenty of fluids and do not exceed 6 capsules within a 24 hour period. If you are taking it for a one-off bout of diarrhoea then your symptoms should improve within 48 hours. If they do not improve, you should speak to a doctor. For IBS sufferers, you can use Loperamide for a period of 2 weeks.

Side Effects

Loperamide side effects

You may experience side effects after taking Loperamide. Common side effects include: 

  • Nausea
  • Constipation
  • Wind
  • Headaches
  • Stomach pain
  • Dizziness
  • Vomiting
  • Rash
  • Dry mouth

Less common side effects include:

  • Bloating
  • Tiredness
  • A burning sensation in the mouth, lips or tongue
  • Itching
  • Sore or tight muscles 
  • Miosis (where the pupils of your eyes narrow) 

Rare side effects include: 

  • Allergic reaction 
  • Various skin rashes: erythema multiforme, Stevens Johnson Syndrome and toxic epidermal necrolysis
  • Megacolon
  • Feeling faint or falling unconscious 
  • A blockage in the intestine
  • Being unable to urinate 

If you experience any of these side effects seek immediate medical attention.   

Contraindications

Loperamide should not be taken if: 

  • You are allergic to any of the ingredients 
  • You are a child under the age of 12
  • You suffer from IBS and are under the age of 18
  • You have a high fever
  • There is blood in your stools
  • You have a medical condition which causes constipation 
  • You have an inflammatory bowel or intestine disease
  • You have stomach pain or diarrhoea caused by Salmonella, Shigella or Campylobacter
  • You have taken antibiotics which has caused you to have diarrhoea 
  • You are breastfeeding

Consult your doctor if: 

  • You have liver problems 
  • You are dehydrated
  • You become constipated after taking Loperamide 
  • You start to notice blood in your stools or develop a fever
  • You are over 40 and have not experienced an IBS flare up in some time
  • You are over 40 and your IBS symptoms are different 

Drug interactions

If you are taking any of the following medications you should consult your doctor before taking Loperamide: 

  • Quinidine
  • Ritonavir
  • Itraconazole
  • Gemfibrozil
  • Ketoconazole
  • Desmopressin
  • Any medicines used to treat the stomach

How to cope with Loperamide side effects

If you experience constipation while taking Loperamide then you should stop taking it and ensure you drink plenty of water. Take it with food if you feel sick and don't over exert yourself if it causes dizziness. Avoid foods like peas, beans, lentils and onions if you are experiencing flatulence and try eating smaller meals more often as this is easier on your digestive system. You can take painkillers to ease headaches. If they last for more than a week let your doctor know. 

Loperamide and alcohol

It's best to avoid drinking alcohol while you are taking Loperamide as it can exacerbate side effects and cause dizziness, tiredness and a lack of concentration. 

Can I take Loperamide with painkillers?

You can take painkillers like Paracetamol and Ibuprofen alongside Loperamide. 

Can you take Loperamide and Metronidazole?

Loperamide and Metronidazole should not be taken together. Exceeding the dose of either medicine can affect the heartbeat and mixing the two together can increase the risk of this happening. If you are already taking Metronidazole then consult your doctor for advice before using Loperamide. 

Q&A

Should I buy Loperamide before I travel?

Loperamide is a suitable remedy for mild to moderate traveller's diarrhoea. While it should not be taken as a preventative measure, you can purchase it before travelling in case you need it. This may be particularly suitable for people with IBS who regularly encounter diarrhoea.

Which countries am I likely to need to take Loperamide for?

Certain countries pose a higher risk for experiencing diarrhoea while you visit. This can be caused by different food hygiene standards or viruses. High risk countries include Asia, the Middle East, Africa, and Latin America. 

Is Loperamide preventative or a cure?

Loperamide cannot be taken as a preventative measure. It should only be used to treat symptoms as they occur. 

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