Pantoprazole brings acid reflux relief within a few days

Pantoprazole decreases the amount of stomach acid produced, relieving symptoms of acid reflux, GORD and heartburn. It takes about 2-3 of daily use to start showing the first effects.

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Strength Quantity Price Stock
20 mg14 tablets£13.49In Stock
20 mg28 tablets£17.99In Stock
40mg14 tablets£14.99In Stock
40mg28 tablets£19.99In Stock
Prices exclude a prescription fee. This treatment requires a quick online consultation,
which a doctor will review to determine if a prescription is appropriate.

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What is Pantoprazole?

Pantoprazole is a medicine which decreases the amount of stomach acid produced. It's used to treat acid reflux, gastroesophageal reflux disease (GERD), soothe heartburn and can also be used to treat stomach ulcers. Pantoprazole is a type of medicine called a proton pump inhibitor.

How does Pantoprazole work?

Pantoprazole works by reducing the amount of acid that is produced by the stomach. Acid reflux occurs when stomach acid travels back up the food pipe, causing a painful burning sensation known as heartburn. If this occurs more than two times a week, it's known as gastroesophageal reflux disease (GERD).

How long does Pantoprazole take to work?

Pantoprazole should start to work after 2-3 days but you may still experience symptoms for up to 4 weeks before the medication takes its full effect.

Is Pantoprazole safe for long term use?

Taking Pantoprazole for longer than three months may cause the magnesium levels in your blood to drop. This can cause:

  • Tiredness
  • Confusion
  • Dizziness
  • Shakiness
  • Muscle twitch
  • Irregular heartbeat

If you take Pantoprazole for a period of a year or more you may experience the following side effects:

  • Bone fractures
  • Gut infections
  • Vitamin B12 deficiency

You should see your doctor regularly if you have been taking Pantoprazole for this long.

What's the difference between acid reflux and heartburn?

Heartburn is the main symptom of acid reflux. This happens when acid from the stomach flows back up the food pipe. Other symptoms may include:

  • Unpleasant taste in your mouth
  • Persistent hiccups
  • Cough
  • Hoarse voice
  • Bad breath
  • Bloating
  • Nausea

It's likely that your symptoms will be more prevalent after eating or when you lie down or bend over.  


Active ingredients

The active ingredient in the medicine is pantoprazole.

Inactive ingredients

The inactive ingredients in Pantoprazole are sodium carbonate (anhydrous), mannitol, crospovidone, povidone K90, calcium stearate.
Coating: hypromellose, povidone K25, titanium dioxide (E171), yellow iron oxide (E172),
propylene glycol, methacrylic acid-ethyl acrylate copolymer (1:1), polysorbate 80, sodium
laurilsulfate, triethyl citrate.


How to take Pantoprazole

Pantoprazole should be taken an hour before a meal. Swallow the tablets whole with a drink of water. Always take it as your doctor has prescribed.

Can you dissolve Pantoprazole in water?

Pantoprazole tablets should be swallowed whole. If you have difficulty swallowing pills, a liquid version of the medicine can be prescribed instead.

How long should I take Pantoprazole for?

If you have purchased 20mg Pantoprazole over-the-counter, take the medicine for 2 weeks. If you don't notice an improvement after this, see your doctor. If you have been prescribed Pantoprazole, the usual treatment period for Acid Reflux and stomach Ulcers is 4-8 weeks.

What should I do if I forget to take Pantoprazole?

If you forget to take your scheduled dose of Pantoprazole then take it as soon as you remember. If you take one tablet a day and you are due to take the next one in less than 12 hours, skip the missed dose. For individuals taking Pantoprazole twice daily do not take a missed dose if your next one is due in less than 4 hours.

What should I do if I take too much Pantoprazole?

If you take too much Pantoprazole by mistake, don't panic. It's unlikely that an extra dose or two will cause you issues but if you notice any of the following symptoms report this to your doctor:

  • Sweating
  • Flushing
  • Faster heartbeat
  • Sleepiness
  • Blurred vision
  • Confusion
  • Agitation


The dose prescribed will depend on what your symptoms are and why you are taking it.

  • Acid reflux and heartburn: 20mg once a day
  • Gastroesophageal reflux disease: 20-40mg a day
  • Stomach ulcers: 20-40mg a day
  • Zollinger- Ellison syndrome: 40-80mg a day

Always take the dose that your doctor or pharmacist has prescribed to treat your symptoms.

Side Effects

Side Effects

Possible side effects include:

  • Benign polyps in the stomach
  • Headaches
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Bloating
  • Flatulence
  • Constipation
  • Stomach pain
  • Dry mouth
  • Rash
  • Itching
  • Weakness
  • Exhaustion
  • Feeling unwell
  • Difficulty sleeping
  • Fractured hip, wrist or spine  
  • Altered taste
  • Blurred vision
  • Muscle pain
  • Changes to weight
  • Fever
  • Depression
  • Disorientation

Serious side effects are rare and may include:

  • Joint pain with a red skin rash which may resemble sunburn
  • Worsening stomach pain, yellow skin and dark coloured urine
  • Pain during urination, difficulty urinating, pain in the lower back and swollen ankles

Seek medical attention if you experience any of these symptoms.

How to cope with Pantoprazole side effects

Headaches usually disappear in the first week of taking Pantoprazole. You can take painkillers to ease the discomfort and ensure you drink plenty of water. Eat plain foods if you feel sick or experience vomiting. Drink frequent sips of water to stay hydrated, including having an upset stomach with diarrhoea. For constipation, incorporate fibre rich foods into your diet.


Pantoprazole is not suitable for:

  • Children under 12
  • Pregnant women
  • People who are allergic to any of the ingredients
  • People with liver problems
  • People scheduled to have an endoscopy

Drug interactions

The following medications may interfere with the effectiveness of Pantoprazole:

  • The antifungals Ketoconazole, Itraconazole and Posaconazole
  • Erlotinib
  • Warfarin
  • Phenprocoumon
  • HIV medications
  • Methotrexate
  • Fluvoxamine
  • Rifampicin
  • St John's wort

Inform your doctor if you are taking any of these before taking Pantoprazole.

Treatment Options

Alternatives to Pantoprazole

Other medications that decrease the amount of stomach acid produced are Lansoprazole, Omeprazole, Esomeprazole and Rabeprazole. These are all proton pump inhibitors that work the same way as Pantoprazole. Antacids are over-the-counter remedies for heartburn such as Gaviscon, Alka Seltzers and Milk of Magnesia. These provide quick relief but are not suitable for long term use.

Can I take Pantoprazole with antacids?

Antacids can be taken alongside Pantoprazole. Wait at least 2 hours before or after taking Pantoprazole before taking any.

Can I take Pantoprazole with painkillers?

Over-the-counter painkillers are fine to take alongside Pantoprazole. Ibuprofen is best taken after a meal to prevent it from having an effect on your stomach.

Can lifestyle changes help?

There are lifestyle changes you can adopt to prevent acid reflux from occurring. These include:

  • Avoid spicy fatty foods or anything acidic
  • Reduce caffeine and alcohol consumption
  • Cut out smoking
  • Avoid eating at least 2-3 hours before going to bed
  • Don't lie down after eating
  • Position yourself so that your head and chest are propped up above your waist while you're sleeping

What causes acid reflux?

There are several common factors which can cause acid reflux. These include:

  • Alcohol
  • Coffee
  • Fatty and spicy foods
  • Acidic foods like citrus fruits and raw onion
  • Smoking
  • Being overweight
  • Stress
  • Pregnancy
  • Anti-inflammatory medicines like ibuprofen
  • A hiatus hernia (this is where a part of your stomach moves up into your chest)

How can I prevent acid reflux?

Acid reflux cannot always be prevented but there are measures you can take to help reduce the possibility of it occurring. Avoiding foods which trigger your symptoms, cutting down on caffeinated drinks and not smoking will help. It's also recommended not to eat too close to bedtime and maintaining a healthy weight. Finding ways to manage and deal with stress may also help to prevent acid reflux.


Pantoprazole and alcohol

Drinking alcohol is not advised while you are taking Pantoprazole. This is because it can trigger acid reflux and cause irritation to your stomach lining.

Can I buy Pantoprazole over-the-counter?

Pantoprazole is available to purchase over the counter as a 20mg dose. If you don't notice an improvement in your symptoms after 2 weeks then see your doctor.

Will Pantoprazole affect my fertility?

There is no evidence to suggest that Pantoprazole can impact fertility.

Will Pantoprazole affect my contraception?

Pantoprazole will not have an effect on the contraceptive pill but it can interfere with ellaOne, a type of the morning after pill.

Can I drive while taking Pantoprazole?  

If you experience any side effects that impair your vision or reflexes, do not drive until you feel better. Pantoprazole can cause dizziness, confusion or blurred vision in some people.

Pantoprazole and pregnancy

Pantoprazole is not suitable for pregnant or breastfeeding women. If you experience acid reflux during this time, speak to your doctor or midwife who can recommend a safe treatment.

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