Trimbow

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Trimbow is a triple therapy inhaler for COPD. It contains three different active ingredients: beclomethasone, formoterol and glycopyrronium bromide. Combining three medications in one inhaler offers a convenient way to take your COPD medications. 

Our prices

Strength Quantity Price Stock
87/5/9 mcg1 inhaler£79.00In Stock
Prices exclude a prescription fee. This treatment requires a quick online consultation,
which a doctor will review to determine if a prescription is appropriate.

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About

What is Trimbow inhaler?

Trimbow is a triple therapy inhaler. That means it contains three different medications in combination. It is used for the treatment of chronic obstructive pulmonary disease (COPD). Many patients with COPD have to take several different inhalers, so combining all three in one inhaler is much more convenient for the patient. Trimbow can also be used with a spacer, to make inhalation easier.

What is Trimbow inhaler used for?

Trimbow is used for the treatment of moderate to severe COPD. There are two key subtypes of COPD: emphysema and chronic bronchitis. Trimbow is used to treat the symptoms of both types.

How does Trimbow work?

Trimbow works in three different ways, as it contains three different ingredients:

  • Beclomethasone is a corticosteroid. It helps to reduce inflammation, which can cause breathing difficulties. 
  • Formoterol is a type of drug known as a long-acting beta-2 agonist (LABA). This means that formoterol works by acting on receptors that cause the airways to relax and open.
  • Glycopyrronium bromide is a muscarinic antagonist. This means that it has similar effects to formoterol, but it works by blocking receptors that would cause the airways to narrow. 

These three medications all help to reduce the symptoms of COPD, making it easier to breathe. 
 

Can you use Trimbow for asthma?

You can use Trimbow for asthma, although generally it would only be prescribed if you have tried other inhalers containing medications known as LABAs (Formeterol, Salmeterol etc.). If these inhalers and a corticosteroid inhaler are not enough to control your asthma symptoms, Trimbow may be an option for you.

What does Trimbow inhaler do?

Trimbow helps to alleviate the symptoms of COPD. It is not a cure and it will not slow the progression of the disease, but it can help to alleviate breathing difficulties associated with COPD. There is currently no cure for COPD, but quitting smoking can dramatically slow the progression of the disease.

How long does it take for Trimbow to work?

Trimbow contains different active ingredients, with different effects. The formoterol and glycopyrronium are a type of medication known as bronchodilators. This means that they allow your airways to relax and widen. You should experience these effects within just a few minutes of taking Trimbow. These effects should last for approximately 12 hours, this is why it is usually recommended that you take Trimbow in the morning and the evening. Alongside this, there is also beclometasone, a corticosteroid. Corticosteroids help to prevent your symptoms. It can take 1 to 3 weeks to have any noticeable effects and can take up to 3 months for the beclometasone to have its full effect.

Ingredients

What does Trimbow contain?

Active ingredients

Trimbow contains three different active ingredients:
Beclometasone dipropionate
Formoterol fumarate dihydrate
Glycopyrronium bromide

 

Inactive Ingredients

The inactive ingredients contained in Trimbow are ethanol anhydrous, hydrochloric acid and norflurane.

Is Trimbow a steroid inhaler?

Trimbow is a combination inhaler containing three different ingredients, one of which is a corticosteroid. Corticosteroids help to reduce inflammation, making it easier to breathe. Steroid inhalers, also known as ‘preventer inhalers’, contain only corticosteroids as active ingredients.

Dosage

Trimbow: How often should you use it?

The recommended dosage for Trimbow is two puffs twice a day. You should take Trimbow at the recommended dose even if you are asymptomatic. This is because Trimbow has both preventative and relieving effects. You should always take Trimbow as directed by your doctor.

When to take Trimbow?

Usually, the recommended dose would be two puffs in the morning and two in the evening. Your doctor may adjust this to better fit your personal circumstances. You should always take Trimbow as instructed by the prescribing physician. If you have any questions about your dosage, it is best to discuss these with your doctor.

Trimbow: How many times a day is normal?

Two puffs twice a day are the standard dose for Trimbow. This is also the maximum dosage. If you feel that you need more than this, you should speak to your doctor as another medication may be more suitable for you. Do not exceed the prescribed dose.

Can you use Trimbow with a spacer?

Trimbow can be used with a spacer. Spacers can make it much easier to inhale the medication properly and they help to ensure that as much medication reaches your lungs as possible, giving you maximum effect.

How to use a Trimbow inhaler

Trimbow may be used with or without a spacer. Please see the instructions below for how to use Trimbow with a spacer. How to take Trimbow without a spacer:

  1. Check the dose counter on the inhaler.
  2. Remove the cap from your Trimbow inhaler and check that it is clean and that there is nothing stuck inside. 
  3. Breathe out slowly and deeply
  4. Hold the inhaler upright and insert the mouthpiece into your mouth. Place the mouthpiece between your teeth, but don’t bite down on it. Form a seal around the mouthpiece with your lips.
  5. Start to breathe in slowly and deeply. Just after you start inhaling, press down on the canister at the top of the inhaler. Continue breathing in slowly and deeply for about 4-5 seconds. If you have difficulty doing this, you may want to speak to your doctor or asthma nurse about using Trimbow with a spacer.
  6. Hold your breath for as long as you can manage, then remove the inhaler from your mouth. 
  7. Breathe out slowly once you have removed the inhaler from your mouth.
  8. Check the dose counter has moved down by one dose. 
  9. Repeat the steps above for the second puff. 

How to use Trimbow inhaler with spacer

Your COPD nurse or doctor should show you how to use your spacer correctly. There can be some variation between different spacers and medications. Trimbow is inhaled through the tidal breath technique, meaning that you breathe normally, but other medications may require different techniques, so always check with your doctor if you are unsure. The instructions below outline how to use a spacer with Trimbow: 

  1. Take the cap off your Trimbow inhaler and check that there is no dirt or debris stuck inside. 
  2. Shake the inhaler vigorously
  3. Insert the inhaler into the end of the spacer, making sure the inhaler is facing upright
  4. Put the mouthpiece of the spacer into your mouth and create a tight seal around it with your lips
  5. Sit or stand up with your back straight and tilt your head back slightly to help the medication reach your lungs
  6. Press down on the top of your inhaler to administer the dose
  7. Breathe normally through the spacer for about 5 breaths 
  8. Remove the spacer from your mouth, disconnect your Trimbow inhaler and replace the cap.

Side Effects

What are the side effects of Trimbow inhaler?

Common side effects, affecting up to 1 in 10 people include: 

  1. A sore throat
  2. Oral thrush
  3. Runny nose or blocked nose
  4. Sneezing
  5. Hoarse voice
  6. Headache
  7. Urinary tract infections (UTIs)


For a full list of side effects, including those that are less common, please see the patient information leaflet included with your medication.

 

When to speak to your doctor

Speak to your doctor immediately if you experience any symptoms of an allergic reaction, such as itching, rash, hives etc. or if you experience side effects affecting your eyes, such as blurred vision or redness. 

Very rarely, Trimbow can have the opposite effect than is intended, causing shortness of breath and wheezing. If this happens, you should stop using Trimbow and use your reliever inhaler immediately to treat the symptoms. Then you should contact your doctor as soon as possible.

Can Trimbow cause weight gain?

Weight gain is not a known side effect of Trimbow. In fact, reduced appetite is a rare side effect of Trimbow, which could result in weight loss for some people.

Can Trimbow cause dizziness?

Dizziness is an uncommon side effect of Trimbow. This means that it affects up to 1 in 100 people taking Trimbow. If you experience dizziness, you should avoid driving or using heavy machinery. 

Can Trimbow cause constipation?

Constipation is not a listed side effect of Trimbow, however diarrhoea is known to affect up to 1 in 100 people taking Trimbow.

Contraindications

Inform the prescribing doctor if any of the following apply to you:

  • Heart conditions 
  • Narrowing of the arteries (arteriosclerosis)
  • Overactive thyroid
  • Low potassium in your blood (hypokalaemia)
  • Liver disease
  • Kidney disease
  • Diabetes
  • Tumour of your adrenal gland (phaeochromocytoma)
  • An eye problem called narrow-angle glaucoma
  • Difficulty urinating
  • A mouth or throat infection
  • You have or have previously been treated for TB (tuberculosis)
  • Chest infection
  • You are expecting to need an anaesthetic in the near future. 

Drug Interactions

You should always inform your doctor of any other medications that you are taking. Some medications can interact with Trimbow producing side effects, which may be dangerous. If you are taking beta-blocker medication such as Atenolol or Propranolol, you must let the doctor know, as beta-blockers can have very dangerous interactions with Trimbow and other asthma/COPD medications.

Treatment Options

Is Trimbow a good inhaler for COPD?

Trimbow is an effective medication for COPD. Like all COPD treatments, it treats the symptoms, but does not cure the disease.

Which is better: Trimbow vs Trelegy?

Trimbow and Trelegy are both ‘triple therapy’ inhalers used in COPD. That means that they each contain three different active ingredients. The key difference between Trimbow and Trelegy is in how you take the inhaler. Trimbow is a type of inhaler known as a pressurized metered dose inhaler. This means that you inhale slowly and deeply to take it. However, Trelegy is a dry powder inhaler. This means that it needs to be inhaled in a quick deep breath. If you struggle to inhale in a short deep breath, Trimbow may be the better inhaler for you. In addition, Trimbow fits on to a spacer, allowing you to breathe normally as you inhale.

Is Trimbow better than Fostair?

Trimbow and Fostair are very similar medications. Fostair contains two active ingredients: beclometasone and formoterol. Trimbow is a triple therapy inhaler, it contains the same active ingredients as Fostair, but also contains glycopyrronium. Which inhaler is better for you will depend upon your individual circumstances. Trimbow is typically prescribed when a combination inhaler like Fostair is not able to control your symptoms sufficiently. 

Trimbow vs Ultibro

There are several differences between Trimbow and Ultibro:

  • Trimbow is a triple therapy inhaler, containing three active ingredients, whereas Ultibro contains only two. 
  • Ultibro does not contain a corticosteroid, but Trimbow does. Corticosteroids help to prevent breathing difficulties, by reducing inflammation. 
  • Ultibro is a dry powder inhaler, whereas Trimbow is a pressurized metered dose inhaler. This means that Ultibro needs to be inhaled in a short deep breath, whereas Trimbow can be inhaled in slow deep breaths. Trimbow can also be used with a spacer, to make inhalation easier. 

Your doctor will discuss your options and prescribe the most suitable inhaler based on your individual circumstances. 

Trimbow vs Symbicort

Symbicort is a combination inhaler, containing budesonide and formoterol. Trimbow, also contains formoterol, but contains glycopyrronium and beclometasone as well. Trimbow would generally be prescribed if a dual-medication like Symbicort does not sufficiently control your symptoms.

Trimbow vs Seretide

Trimbow and Seretide are both prescribed for the treatment of COPD, however Trimbow contains three active ingredients, whereas Seretide only contains two. This means that Trimbow is generally only prescribed when a dual-therapy inhaler, like Seretide is insufficient.

Trimbow vs Relvar

Relvar contains two active ingredients, whereas Trimbow contains three. For this reason, Trimbow is more likely to be prescribed when two-medication inhalers like Relvar, do not give sufficient control of your symptoms. In addition, Relvar is only available as a dry powder inhaler. This means that it needs to be inhaled in a short deep breath. If you struggle with this inhaler technique, a pressurized metered dose inhaler, such as Trimbow, may be more suitable for you.

Q&A

Where can I buy a Trimbow inhaler?

Trimbow is available on repeat prescription from Dr Felix. Simply complete our online consultation form to get started. This will be reviewed by our doctor and if suitable our pharmacy will dispatch the medication directly to your door. 

Can you use Trimbow for bronchiectasis?

Trimbow is not recommended for use in bronchiectasis. Short term use of bronchodilators (medications that relax your airway) is recommended in patients with a severe flare-up of bronchiectasis symptoms. Trimbow does contain a bronchodilator, but it also contains other medications that are not appropriate for bronchiectasis.

How to store Trimbow inhaler?

Trimbow will be kept in a fridge before it is dispensed to you by the pharmacy, however, you do not need to keep Trimbow in a fridge yourself. Trimbow can be kept safely for up to 2 months providing the temperature does not exceed 25°C. If you travel to a hot climate, try to keep your inhaler in a cool place, where the temperature would be below 25°C.

What colour is Trimbow inhaler?

Trimbow inhalers are dark grey with a red cap.

Where is Trimbow manufactured?

Trimbow is made by Chiesi, which has manufacturing sites in Italy, Austria and France.

Who makes Trimbow?

Trimbow is manufactured by Chiesi Respiratory, a branch of the Chiesi Group.

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