TriRegol is a type of combined contraceptive pill containing both oestrogen and progestogen hormones which help to prevent unwanted pregnancy.
The pill contains ethinylestradiol and levonorgestrel, synthetic versions of the oestrogen and progesterone that exist naturally in your body. TriRegol primarily works by reducing the chance of the ovaries releasing an egg (ovulation). The hormones in the pill also thicken the mucus surrounding the entrance to the cervix, preventing sperm from entering, and they thin the lining of the womb (endometrium), making it difficult for a fertilised egg to implant into the womb.
TriRegol is over 99% effective if it is taken correctly all of the time. If the pill is not taken correctly all of the time, it is around 91% effective. This means that with typical use, 9 women out of every 100 taking TriRegol may fall pregnant. With perfect use, only 1 out of every 100 women using TriRegol will fall pregnant.
TriRegol will start to work right away if you take it on the first day of a natural period. You can also start it at another time in your cycle if you are sure you are not pregnant, but you will need to use condoms for the first 7 days of pill-taking to prevent pregnancy.
TriRegol can also be used to regulate your period and can help to ease premenstrual syndrome (PMS). Your periods might also be lighter, and less painful. Some women find that phasic pills such as TriRegol cause fewer hormonal side effects such as headaches and mood changes than monophasic combined pills.
TriRegol can be used to delay your period while you’re taking it. You can do this by skipping the pill-free week between packs and starting the next one right away.
There are numerous types of contraceptive pills available and you may need to try a few different brands before finding one that works for you. If you are taking a different form of the combined pill and are changing to TriRegol then you should finish your current pill strip and begin taking TriRegol the next day without taking a break. Speak with your doctor for more information on how to switch pills safely.
You can switch from the progestogen-only pill at any time but TriRegol won't start to work right away. You will need to use an additional barrier method of contraception for the first 7 days.
If you have been sick or had diarrhoea within 4 hours of taking TriRegol then your contraception may not work. This is because the pill may not have been fully absorbed by your body. If you are unwell, you should continue to take your TriRegol as normal, but you should use extra precautions (condoms) for the duration of illness, and until you have been symptom-free for 7 days.
When you stop taking the pill, you can then get pregnant at any time. It's recommended to wait until your natural period returns; which may be 1–2 months. Talk to your GP or family planning clinic if you are trying to get pregnant. They will be able to advise you on how to come off the pill safely and any steps you can take to ensure you have a healthy conception.
The active ingredients contained in TriRegol are ethinylestradiol and levonorgestrel. There are different amounts of these synthetic hormones depending on where you are in the pack:
The other ingredients are colloidal anhydrous silica, magnesium stearate, talc, maize starch, lactose monohydrate, carmellose sodium, povidone K30, macrogol, copovidone, calcium carbonate, sucrose, red iron oxide (E172), titanium dioxide (E171) and yellow iron oxide (E172).
If it has been 12 hours or more since you were due to take it then follow the instructions for a missed pill that is contained in the pack. Where you are in your pack will dictate what action you should take:
If there have been any worries about not taking the pill correctly or missing pills, speak to your healthcare provider.
If you have taken your pill up to 12 hours later than usual, your contraception will not be affected. Ensure you take the rest of your pills on time. If it has been more than 12 hours since your scheduled pill time, follow the instructions below for ‘what should I do if I miss a pill?’
TriRegol is usually safe to take for as long as you need it. Taking the combined pill increases the risk of blood clots for all women. If you have a medical condition which increases your risk of blood clots (such as having had a blood clot before or suffering from migraines with aura), or if you are older, obese or a smoker, you may not be suitable for combined hormonal contraception. Your doctor will assess your medical history before prescribing you the pill.
If anything changes in your medical history or if you develop any new conditions, you should speak with your doctor or pharmacist to check this pill is still suitable for you
Your natural period usually returns within 2–4 weeks of stopping taking TriRegol. It may take a few months for your cycle to return to its natural rhythm.
You should ideally start taking TriRegol on the first day of your period as you will then be protected from pregnancy right away. If this isn't possible, it’s recommended that you start it on days 2–5 of your period, however, in this case, you will need to use condoms, or another additional contraceptive, for the first seven days.
TriRegol can be taken at any time of the day but it should be taken at the same time each day. Try to choose a time which is convenient for you and that will be easy to remember. Setting an alarm or reminder on your phone may help you to get into the routine of it. Each strip of pills contains 21 tablets. When you reach the end of one strip, wait 7 days before starting the next strip. This is when you will likely have a withdrawal bleed, similar to a period.
To use TriRegol for period delay, skip the 7 day break in between pill packs. This will delay your period until the following month. It's recommended to ask your doctor for advice about delaying your period with TriRegol.
Common side effects include:
Uncommon side effects may include:
Rare side effects may include:
Do not take TriRegol if:
Talk to your doctor before taking TriRegol if any of the following apply to you:
Tell your doctor if you are taking any of the following medicines as they may interfere with the way TriRegol works:
Always tell your doctor about any other medications you are taking, or planning to take, to ensure the combination is safe. This includes over-the-counter medications and recreational drugs.
TriRegol differs from the mini-pill as it contains two types of hormones; oestrogen and progestogen. The mini-pill only has a progestogen as the active ingredient and is often referred to as the progestogen-only pill. The mini-pill may produce fewer side effects and doesn't pose as many health risks as the combined pill. This means it may be suitable for women with high blood pressure or those who experience unpleasant side effects with the combined pill.
Other types of the combined pill which contain the same hormonal ingredients are:
Dr Felix stocks all available types of the contraceptive pill in the UK, including combined pills and mini-pills. Long term reversible contraceptives are available from your GP or family planning clinic. These include the copper IUD, hormonal IUS, implant and injection.